Results 111 to 120 of about 4,213,243 (302)
Analysis of an unswept propfan blade with a semiempirical dynamic stall model [PDF]
The time history response of a propfan wind tunnel model with dynamic stall is studied analytically. The response obtained from the analysis is compared with available experimental data.
Kaza, K. R. V., Reddy, T. S. R.
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Estimation of wind force time-history using limited floor acceleration responses by modal analysis
Time-history analyses are usually performed to design and examine the performance of tall structures subjected to strong wind loading. An accurate estimate of the time history of wind forces is required to carry out time-history analysis. However, previous studies conducted to estimate the time-history of wind forces require a lot of priori information,
Daiki Sato +5 more
openaire +2 more sources
Three methods for the description of the temporal response to a SH plane impulsive seismic wave in a soft elastic layer overlying a hard elastic substratum [PDF]
We treat the case of a flat stress-free surface (i.e., the ground in seismological applications) separating air from a homogeneous, isotropic, solid substratum overlain by a homogeneous, isotropic, solid layer (in contact with the ground) solicited by a ...
Wirgin, Armand
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The assessment of the seismic performance of transportation infrastructures is of primary importance for the management of the aftermath of an earthquake.
Carlo Pettorruso, Virginio Quaglini
doaj +1 more source
WINSTON-BATAN: A SEISMOLOGICAL GROUND-MOTION ANALYSIS CODE
A thorough understanding of an earthquake is very important to provide a descriptive knowledge and in the same time as a prescriptive knowledge for the future development.
Yuliastuti Yuliastuti +2 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

