Results 41 to 50 of about 4,213,243 (302)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

ANTARES: Progress towards building a `Broker' of time-domain alerts

, 2016
The Arizona-NOAO Temporal Analysis and Response to Events System (ANTARES) is a joint effort of NOAO and the Department of Computer Science at the University of Arizona to build prototype software to process alerts from time-domain surveys, especially ...
Axelrod, Tim, Jenness, Tim, Kececioglu, John, Matheson, Thomas, Narayan, Gautham, Ridgway, Stephen, Saha, Abhijit, Scheidegger, Carlos, Seaman, Robert, Snodgrass, Richard, Taylor, Clark, Toeniskoetter, Jackson, Wang, Zhe, Welch, Eric, Yang, Shuo, Zaidi, Tayeb   +15 more
core   +1 more source

Dimensional analysis of yielding and pounding structures for records without distinct pulses [PDF]

, 2009
The seismic response of two fundamental mechanical configurations of earthquake engineering, the elastic–plastic system and the pounding oscillator, is revisited with the aid of dimensional analysis.
Dimitrakopoulos, E. G., Kappos, A. J., Makris, N.   +2 more
core   +2 more sources

A cross-sectional study of predatory publishing emails received by career development grant awardees [PDF]

, 2019
OBJECTIVE: To investigate the scope of academic spam emails (ASEs) among career development grant awardees and the factors associated with the amount of time spent addressing them.
Bennett, William E., Carroll, Aaron E., Cheng, Erika R., Russell, Christopher J., Wilkinson, Tracey A.   +4 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Fundamental study of damping models with enhanced frequency independence in nonlinear seismic response analysis

Japan Architectural Review
Causal hysteretic damping, extended Rayleigh damping, and uniform damping models exhibit frequency‐independent damping ratios over a wide frequency range.
Akira Ota, Naohiro Nakamura, Kunihiko Nabeshima, Yoshihiro Mogi, Masafumi Kawabata   +4 more
doaj   +1 more source

Seismic Behavior of High-Rise Buildings Having Transfer Elements

Electronic Journal of Structural Engineering, 2023
This paper investigates the seismic behavior of high-rise buildings having transfer elements. Three constructed reinforced concrete (RC) buildings having either transfer slabs or transfer girders were analyzed using the response spectrum (RS) and time ...
El-Sayed Z. El-Bayome, Ahmed M. Abd El-Salam, Osama O. El-Mahdy, Hala.M Refaat   +3 more
doaj  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Extended Rayleigh Damping Model

Frontiers in Built Environment, 2016
In dynamic analysis, frequency domain analysis can be used if the entire structure is linear. However, time history analysis is generally used if nonlinear elements are present.
Naohiro Nakamura
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source