Results 181 to 190 of about 6,289,366 (311)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Study Protocol for a Randomized, Controlled Trial: Improving Glucose Time-in-Range in Diabetes in African Youth (DAYTime). [PDF]

open access: yesMethods Protoc
Piloya-Were T   +7 more
europepmc   +1 more source

The Empirical Properties of Some Popular Estimators of Long Memory Processes [PDF]

open access: yes
We present the results of a simulation study into the properties of 12 different estimators of the Hurst parameter, H, or the fractional integration parameter, d, in long memory time series.
Jennifer Brown   +3 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Volume measurement using 3D Range Imaging

open access: yes, 2010
The use of 3D Range Imaging has widespread applications. One of its applications provides us the information about the volumes of different objects. In this paper, 3D range imaging has been utilised to find out the volumes of different objects using two ...
Shrivastava, Vipul   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hemoglobin A1c time-in-range, mortality, and diabetes complications in older adults with diabetes. [PDF]

open access: yesBMJ Open Diabetes Res Care
Conlin PR   +8 more
europepmc   +1 more source

Long range financial data and model choice [PDF]

open access: yes
Long range financial data as typified by the daily returns of the Standard and Poor's index exhibit common features such as heavy tails, long range memory of the absolute values and clustering of periods of high and low volatility.
Davies, Paul Lyndon
core  

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