Results 141 to 150 of about 1,528,850 (317)
Infant mortality rates: Time trends and fractional integration
, 2011 This paper examines the time trends in infant mortality rates in a number of countries in the 20th century. Rather than imposing that the error term is a stationary I(0) process, we allow for the possibility of fractional integration and hence for a much
Caporale, GM, Gil-Alana, LA
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Whither a Europe of the Regions? Minority nationalist parties and the challenges of European integration [PDF]
, 2007 [From the introduction]. This paper argues that even though in the current climate of European integration, the prospects for a Europe of the Regions are dismal indeed, it is too soon to herald the end of minority nationalist support for European ...
Elias, Anwen.
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
What Drives the Regional Integration of Emerging Stock Markets? [PDF]
This study explores the fundamental driving forces of regional equity market integration. The determinant factors are categorized into three dimensions: local, regional and world instrumental variables.
Khaled Guesmi
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Market Integration, Efficiency, and Interconnectors: The Irish Single Electricity Market
, 2012 Interconnections can be an effective way to increase competition and improve market integration in concentrated wholesale electricity markets with limited participants.
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Space-time adaptivity in the XBraid library
, 2017 Since clock speeds are no longer increasing, time integration is becoming a sequential bottleneck. The multigrid reduction in time (MGRIT) algorithm is an approach for exploiting parallelism in the time dimension that is designed to build on existing ...
Falgout, Robert
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Globalization, Regional Integration and the EU: Pleadings for a Broader Perspective. ZEI Discussion Papers C162, 2006 [PDF]
, 2006 [From the Introduction]. Whether we agree to more positive or rather skeptical positions on globalization, it is assumable that globalization and regional integration are related issues.
Janowski, Cordula.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source