Results 121 to 130 of about 1,528,850 (317)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Timing and Integration of Directional Cues

open access: yesInternational Journal of Social Robotics
Abstract Robots that share environments with people should communicate their directional intentions so that people can anticipate their future directions. In the current paper, the aim is to find whether using multiple cues at the same time improves the predictability of the robot. In the first experiment, participants were shown videos of an
Margot M. E. Neggers   +3 more
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Multiple Lebesgue integration on time scales

open access: yesAdvances in Difference Equations, 2006
We study the process of multiple Lebesgue integration on time scales. The relationship of the Riemann and the Lebesgue multiple integrals is investigated.
Guseinov Gusein Sh, Bohner Martin
doaj  

Multi-level urban models: Integration across space, time and policies

open access: yesJournal of Transport and Land Use, 2018
Urban and regional models have been developed for different policy fields at different levels of spatial and temporal resolution. But it has become apparent that policies interact across space and time and need to be modelled together.
Michael Wegener, Klaus Spiekermann
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Is the EU internal market suffering from an integration deficit? Estimating the 'home-bias effect.' CEPS Working Document No. 348, May 2011 [PDF]

open access: yes, 2011
As an alternative to measuring the extent of market integration, ‘home-bias’ indicates the degree to which economic agents ‘over-prefer’ to transact with domestic agents rather than agents from other EU countries. Such an exclusive preference is measured
Pacchioli, Consuelo., Consuelo Pacchioli
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Price convergence and market integration in Russia [PDF]

open access: yes
After a period of growing disconnectedness of regional markets following the 1992 price liberalization in Russia, a process of improvement in market integration started since about 1994. This paper analyzes the spatial pattern of goods market integration
Konstantin Gluschenko
core  

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