Results 81 to 90 of about 749,885 (297)

Discussion: Time-Symmetric Quantum Counterfactuals [PDF]

open access: yes, 2003
There is a trend to consider counterfactuals as invariably time-asymmetric. Recently, this trend manifested itself in the controversy about validity of counterfactual application of a time-symmetric quantum probability rule.
Vaidman, Lev
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Time interval measurement module implemented in SoC FPGA device

open access: yes, 2016
We presents the design and test results of a picosecond-precision time interval measurement module, integrated as a System-on-Chip in an FPGA device. Implementing a complete measurement instrument of a high precision in one chip with the processing unit ...
Szplet, R.   +3 more
core   +1 more source

Functional Interval Estimation for Continuous-Time Linear Systems

open access: yes, 2023
International audienceThis paper presents a functional interval estimation method for continuous-timesystems subject to disturbances and noise. First, a robust functional observer is synthesised to attenuate the effects of uncertainties.
Raïssi, Tarek   +4 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

An on-chip short-time interval measurement technique for testing high-speed communication links

open access: yes, 2001
In this paper, we present a BIST scheme for on-chip short-time interval measurement intended for characterizing the time-domain specifications, e.g., the rise/fall time of modern high-speed communication transceivers.
Huang, J. L., Cheng, K. T.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

High resolution time interval counter

open access: yes, 1995
In recent years, we have developed two types of high resolution, multi-channel time interval counters. In the NIST two-way time transfer MODEM application, the counter is designed for operating primarily in the interrupt-driven mode, with 3 start ...
Zhang, Victor S.   +2 more
core  

On-chip short-time interval measurement system for high-speed signal timing characterization

open access: yes, 2005
In this paper, we present an on-chip short-time interval measurement circuit to characterize the ever-faster communication systems. The proposed circuit consists of time parameters extraction subcircuit and measurement subcircuit, which contain a charge ...
Xia, Tian, Lo, Jien Chung
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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