Results 41 to 50 of about 792,099 (261)
The increasing penetration of distributed energy resources (DERs) introduces significant operational uncertainties, challenging the reliability and robustness of conventional protection coordination in distribution networks.
Jheng-Lun Jiang +2 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
In an electrical power system, the coordination of the overcurrent relays plays an important role in protecting the electrical system by providing primary as well as backup protection. To reduce power outages, the coordination between these relays should
Abdul Wadood +4 more
doaj +1 more source
Distribution systems continue to grow and becoming more complex with increasing operational challenges such as protection miscoordination. Initially, conventional methods were favoured to solve overcurrent relay coordination problems; however, the ...
Sethembiso Nonjabulo Langazane +1 more
doaj +1 more source
INVERSE DEFINITE MINIMUM TIME RELAY COORDINATION IN RADIAL TRACTION SYSTEM
For stable and reliable operation of power system, the coordination of relays plays an important role. In order to achieve fast and selective protection, the relays are to be coordinated through appropriate relay settings with correct grading margins ...
G. Babu +2 more
semanticscholar +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
In electrical engineering problems, bio- and nature-inspired optimization techniques are valuable ways to minimize or maximize an objective function. We use the root tree algorithm (RTO), inspired by the random movement of roots, to search for the global
Abdul Wadood +6 more
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
We are looking at comparison of two action integrals and we identify the Lagrangian multiplier as setting up a constraint equation (on cosmological expansion).
A. Beckwith
semanticscholar +1 more source

