Results 121 to 130 of about 22,430,852 (308)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Qualitative Outcomes on Monotone Iterative Technique and Quasilinearization Method on Time Scale
AxiomsIn this paper, a nonlinear dynamic equation with an initial value problem (IVP) on a time scale is considered. First, applying comparison results with a coupled lower solution (LS) and an upper solution (US), we improved the quasilinearization method ...
Şahap Çetin +2 more
doaj +1 more source
Trade balance and terms of trade in U.S.: a time-scale decomposition analysis [PDF]
The aim of this paper is to provide evidence on the nature of the relationship between the terms of trade and the trade balance for US on a scale-by-scale basis using wavelet analysis.
Marco Gallegati, Luca De Benedictis
core
Subgrid-scale contributions to Lagrangian time correlations in isotropic turbulence
, 2009 The application of large-eddy simulation (LES) to particle-laden turbulence raises such a fundamental question as whether the LES with a subgrid scale (SGS) model can correctly predict Lagrangian time correlations (LTCs).
陆利蓬, 何国威, 张健
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Multi-Time Scale Analysis of Runoff Variation of Kaidu River over Past 60 Years
Renmin ZhujiangThe pattern analysis of the long-sequence river runoff evolution holds crucial importance for the scientific planning and rational utilization of surface water resources.
WEI Guanghui +3 more
doaj
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source