Results 221 to 230 of about 22,430,852 (308)

Time Scale Calculus: a new approach to multi-dose pharmacokinetic modeling. [PDF]

J Pharmacokinet Pharmacodyn
Arteaga-Bejarano JR, Torres S.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer. [PDF]

Bull Math Biol
Yang Q, Traulsen A, Altrock PM.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Continuous Biosensor Based on Particle Motion: How Does the Concentration Measurement Precision Depend on Time Scale? [PDF]

ACS Sens
Lubken RM, Lin YT, Haenen SRR, Bergkamp MH, Yan J, Nommensen PA, Prins MWJ.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Long Time Scale Molecular Dynamics Simulation of Magnesium Hydride Dehydrogenation Enabled by Machine Learning Interatomic Potentials. [PDF]

ACS Appl Energy Mater
Morrison O, Uteva E, Walker GS, Grant DM, Ling S.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Dynamic connectivities of plant metacommunities at a millennial time-scale: the Beringia testbed

Herzschuh U, Stoof-Leichsenring KR, Farkas LZ, Liu Y, Liu S, Böhmer T, Baisheva I, Biskaborn BK, Courtin J, Diekmann B, Epp LS, von Hippel B, Huang S, Huang Y, Jia W, Kaufman DS, Meyer H, Melles M, Meucci S, Pestryakova LA, Schulte L, Wagner B, Wang Z, Zakharov ES.   +23 more
europepmc   +1 more source

Predicting Long-Time-Scale Kinetics under Variable Experimental Conditions with Kinetica.jl. [PDF]

J Chem Theory Comput
Gilkes J, Storr MT, Maurer RJ, Habershon S.   +3 more
europepmc   +1 more source