Results 61 to 70 of about 3,595,948 (318)

New results for time reversed symplectic dynamic systems and quadratic functionals

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
In this paper, we examine time scale symplectic (or Hamiltonian) systems and the associated quadratic functionals which contain a forward shift in the time variable.
Roman Simon Hilscher, Petr Zemanek
doaj   +1 more source

Symmetric differentiation on time scales

open access: yesApplied Mathematics Letters, 2013
We define a symmetric derivative on an arbitrary nonempty closed subset of the real numbers and derive some of its properties. It is shown that real-valued functions defined on time scales that are neither delta nor nabla differentiable can be symmetric differentiable.
Brito da Cruz, A. M. C.   +2 more
openaire   +4 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Nonlinear first-order periodic boundary-value problems of impulsive dynamic equations on time scales

open access: yesElectronic Journal of Differential Equations, 2012
By using the fixed point theorem in cones, in this paper, existence criteria for single and multiple positive solutions to a class of nonlinear first-order periodic boundary value problems of impulsive dynamic equations on time scales are obtained. An
Wen Guan, Dun-Gang Li, Shuang-Hong Ma
doaj  

Qualitative aspects of Volterra integro-dynamic system on time scales

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2013
This paper deals with the resolvent, asymptotic stability and boundedness of the solution of time-varying Volterra integro-dynamic system on time scales in which the coefficient matrix is not necessarily stable.
Vasile Lupulescu   +2 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Increasing the Utilization of Transmission Lines Capacity by Quasi-Dynamic Thermal Ratings

open access: yesEnergies, 2019
The power grid is under pressure to maintain a reliable supply because of constrained budgets and environmental policies. In order to effectively make use of existing transmission lines, it is important to accurately evaluate the line capacity.
Fan Song   +4 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Global Bifurcation on Time Scales

open access: yesJournal of Mathematical Analysis and Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Davidson, Fordyce A., Rynne, Bryan P.
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

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