Results 191 to 200 of about 2,965,478 (248)

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

open access: yesAging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

White Christian Nationalism: Adult Education and Threats to Democracy

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult education has a historical and ongoing commitment to fostering democratic relationships, demonstrated by the tendency of adult education to be called upon when social change and realignment are most desirable. This article considers the philosophical and pragmatic possibilities for adult education at this moment, when White Christian ...
Ralf St. Clair, Lyn Tett, Rob Black
wiley   +1 more source

Adult Education Confronting White Christian Nationalism: A Thematic Analysis

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT As a way to conclude, this article elaborates key themes that emerged from the collected articles in this volume. Each article carries its own important message about the role of adult education in confronting White Christian nationalism, while here, Prins and Carr‐Chellman offer a thematic interpretation of the volume as a whole. These themes
Esther Prins, Davin Carr‐Chellman
wiley   +1 more source

Unlearning and Deradicalizing From White Christian Nationalism: Implications for Adult Learning and Education

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Since the January 2021 attack on the US Capitol, the influence of White Christian nationalism (WCN) has become even more pronounced and concerning. Adult educators and the public need a better understanding of whether and how WCN can be unlearned, and the roles ordinary citizens and adult educators can play in this process.
Esther Prins
wiley   +1 more source

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard   +7 more
wiley   +1 more source

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