Results 61 to 70 of about 1,023,532 (301)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Asymptotic behavior of nonoscillatory solutions of higher-order integro-dynamic equations [PDF]
Opuscula Mathematica, 2014 In this paper, we establish some new criteria on the asymptotic behavior of nonoscillatory solutions of higher-order integro-dynamic equations on time scales.
Martin Bohner +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Lyapunov inequalities for time scales
Journal of Inequalities and Applications, 2002 The theory of time scales has been introduced in order to unify discrete and continuous analysis. We present a Lyapunov inequality for Sturm-Liouville dynamic equations of second order on such time scales, which can be applied to obtain a disconjugacy ...
Ridenhour Jerry +2 more
doaj
An Opial-Type Inequality on Time Scales
Abstract and Applied Analysis, 2013 We establish some new Opial-type inequalities involving higher order delta derivatives on time scales. These extend some known results in the continuous case in the literature and provide new estimates in the setting of time scales.
Qiao-Luan Li, Wing-Sum Cheung
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Impulsive Diffusion Equation on Time Scales
International Journal of Analysis and Applications, 2018 Application of boundary value problems (BVP’s) on an arbitrary time scale T is a fairly new and important subject in mathematics. In this study, we deal with an eigenvalue problem for impulsive diffusion equation with boundary conditions on T.
Tuba Gulsen +3 more
doaj +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source