Results 61 to 70 of about 305,215 (245)

Optimal Caching and Routing in Hybrid Networks

open access: yes, 2014
Hybrid networks consisting of MANET nodes and cellular infrastructure have been recently proposed to improve the performance of military networks. Prior work has demonstrated the benefits of in-network content caching in a wired, Internet context.
Dehghan, Mostafa   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Enhanced System Design and Scheduling Strategy for Switches in Time-Sensitive Networking

open access: yesIEEE Access, 2021
Time-Sensitive Networking (TSN) is a new set of amendments that guarantee the quality of service (QoS) of time-critical and safety-critical Ethernet applications.
Zhipeng Cao   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Online Security in the Middle East and North Africa: A Survey of Perceptions, Knowledge, and Practice [PDF]

open access: yes, 2011
Digital communication has become a more perilous activity, particularly for activists, political dissidents, and independent media. The recent surge in digital activism that has helped to shape the Arab spring has been met with stiff resistance by ...
Ethan Zuckerman   +4 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

A Microservices-Based Control Plane for Time-Sensitive Networking

open access: yesFuture Internet
Time-Sensitive Networking (TSN) aims to provide deterministic communications over Ethernet. The main characteristics of TSN are bounded latency and very high reliability, thus complying with the strict requirements of industrial communications or ...
Anna Agustí-Torra   +4 more
doaj   +1 more source

The Boston Girls Sports & Physical Activity Project: Final Report to the Barr Foundation [PDF]

open access: yes, 2007
The main goal of the three-year Boston Girls' Sports & Physical Activity Project (BGSPAP) was to create an integrated and sustainable network of community-based programs that use sports and physical activity to favorably influence the physical ...

core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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