Results 121 to 130 of about 28,610,872 (373)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

DYNAMIC / CHRONOLOGICAL (TIME) SERIES [PDF]

open access: yesRevista Română de Statistică, 2012
Time series, which emphasize the temporal characteristic of phenomena, are an important in the context of macro-economical analyses. Specific to the dynamic series is the fact that they are defined for complexentities, characterized by a high level of ...
Constantin ANGHELACHE, Alexandru MANOLE
doaj  

Studies in astronomical time series analysis. II - Statistical aspects of spectral analysis of unevenly spaced data

open access: yes, 1982
Detection of a periodic signal hidden in noise is frequently a goal in astronomical data analysis. This paper does not introduce a new detection technique, but instead studies the reliability and efficiency of detection with the most commonly used ...
J. Scargle
semanticscholar   +1 more source

15. Time series

open access: yesStochastic Processes and their Applications, 1984
K. Sureshchandra, G. Gopal
  +7 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Eigen-entropy based time series signatures to support multivariate time series classification

open access: yesScientific Reports
Most current algorithms for multivariate time series classification tend to overlook the correlations between time series of different variables. In this research, we propose a framework that leverages Eigen-entropy along with a cumulative moving window ...
Abhidnya Patharkar   +6 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

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