Results 121 to 130 of about 3,160,678 (291)
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla+4 more
wiley +1 more source
Time and memory in time series analysis [PDF]
Flávia Reis de Andrade+1 more
doaj +1 more source
Autocorrelation functions for point-process time series [PDF]
This article introduces autocorrelograms for time series of point processes. The method is computationally simple, based on binning rather than smoothing. The ability of the method to detect common time series patterns is shown by simulation, and two examples of application to temporal and spatial point processes series are given.
arxiv
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
CO and CO2 daily time series and time series of wind speed
The global CO2 has increased rapidly because of the vast use of fossil fuels over past 40 years. CO, co-emitted with CO2, also increased during this period.
Changgong Shan, Wei Wang
doaj
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley +1 more source
Understanding Time Series Anomaly State Detection through One-Class Classification [PDF]
For a long time, research on time series anomaly detection has mainly focused on finding outliers within a given time series. Admittedly, this is consistent with some practical problems, but in other practical application scenarios, people are concerned about: assuming a standard time series is given, how to judge whether another test time series ...
arxiv
Spectral Analysis and Linear Prediction of Meteorological Time Series [PDF]
Richard H. Jones
openalex +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source