Results 41 to 50 of about 31,033 (265)

A novel time-frequency multilayer network for multivariate time series analysis

New Journal of Physics, 2018
Unveiling complex dynamics of natural systems from a multivariate time series represents a research hotspot in a broad variety of areas. We develop a novel multilayer network analysis framework, i.e.
Weidong Dang, Zhongke Gao, Dongmei Lv, Mingxu Liu, Qing Cai, Xiaolin Hong   +5 more
doaj   +1 more source

Identifying Chaotic FitzHugh–Nagumo Neurons Using Compressive Sensing

Entropy, 2014
We develop a completely data-driven approach to reconstructing coupled neuronal networks that contain a small subset of chaotic neurons. Such chaotic elements can be the result of parameter shift in their individual dynamical systems and may lead to ...
Ri-Qi Su, Ying-Cheng Lai, Xiao Wang
doaj   +1 more source

Measuring dynamical phase transitions in time series

Physical Review Research
There is a growing interest in methods for detecting and interpreting changes in experimental time-evolution data. Based on measured time series, the quantitative characterization of dynamical phase transitions at bifurcation points of the underlying ...
Bulcsú Sándor, András Rusu, Károly Dénes, Mária Ercsey-Ravasz, Zsolt I. Lázár   +4 more
doaj   +1 more source

Evidence of self-organized criticality in time series by the horizontal visibility graph approach

Scientific Reports, 2022
Determination of self-organized criticality (SOC) is crucial in evaluating the dynamical behavior of a time series. Here, we apply the complex network approach to assess the SOC characteristics in synthesis and real-world data sets.
Bardia Kaki, Nastaran Farhang, Hossein Safari   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Temporal network analysis using zigzag persistence

EPJ Data Science, 2023
This work presents a framework for studying temporal networks using zigzag persistence, a tool from the field of Topological Data Analysis (TDA). The resulting approach is general and applicable to a wide variety of time-varying graphs.
Audun Myers, David Muñoz, Firas A Khasawneh, Elizabeth Munch   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Can Recurrence Quantification Analysis Be Useful in the Interpretation of Airborne Turbulence Measurements?

Geophysical Research Letters
In airborne data or model outputs, clouds are often defined using information about Liquid Water Content (LWC). Unfortunately LWC is not enough to retrieve information about the dynamical boundary of the cloud, that is, volume of turbulent air around the
Stanisław Król, Alan Blyth, Steven Böing, Leif Denby, Tom Lachlan‐Cope, Szymon P. Malinowski   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source