Results 91 to 100 of about 751,571 (292)
Advanced Science, EarlyView.Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han +6 more
wiley +1 more source
Carbon footprint forecasting using time series data mining methods: the case of Turkey. [PDF]
Environ Sci Pollut Res Int, 2021 Akyol M, Uçar E.
europepmc +1 more source
Echo state network for occupancy prediction and pattern mining in intelligent environment [PDF]
, 2009 Pattern analysis and prediction of sensory data is becoming an increasing scientific challenge and a massive economical interest supports the need for better pattern mining techniques.
Langensiepen, C +4 more
core
Visual Mining of Spatial Time Series Data [PDF]
, 2004 CommonGIS is a system comprising a number of tools for visual data analysis. In this paper we demonstrate our recent developments for analysis of spatial time series data.
Gennady Andrienko +2 more
openaire +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, EarlyView.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, EarlyView.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
Advanced Science, EarlyView.SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Durable Thin‐Film Porous Transport Electrodes for High Current Density PEM Water Electrolysis
Advanced Science, EarlyView.Water electrolysis using porous transport electrodes with sputter‐deposited, ionomer‐free thin films of rutile IrO2 catalyst suppresses Ir dissolution by >10x over other forms of IrOx. The rutile IrO2 catalyst prepared by this readily scalable electrode synthesis method provides stable cell operation at 3 A cm−2 while using low Ir loading (0.4 mg Ir cm−
James L. Young +18 more
wiley +1 more source
Review of Outlier Detection Algorithms [PDF]
Jisuanji kexueOutlier detection,as an important research direction in the field of data mining,aims to discover data points in a dataset that are different from the majority and have potential analytical value,assistresearchers in identifying potential issues in the ...
KONG Lingchao, LIU Guozhu
doaj +1 more source
Advanced Science, EarlyView.Enhancing the utilization efficiency of nutrients recovered from wastewater is achieved through hydrogel modification by biochar. The strategy improves nutrient binding to hydrogels via electron transfer at heterointerfaces, thereby reducing nutrient release rate.
Hao Hu +7 more
wiley +1 more source