Results 101 to 110 of about 751,571 (292)

Study on Visual Techniques of Potential Pattern Discovery for Time Series Data

MATEC Web of Conferences, 2018
Sequential pattern mining is always a very important branch of time series data mining. The pattern mining with visual means can be used to extract the knowledge of time series data more intuitively. Based on the research content, this paper analyzes the
Xu Dalin, Wei Yingmei
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AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Time series data mining methods

, 2015
Today, real world time series data sets can take a size up to a trillion observations and even more. Data miners’ task is it to detect new information that is hidden in this massive amount of data. While well known techniques for data mining in cross sections have been developed, time series data mining methods are not as sophisticated and established ...
openaire   +1 more source

Defect Engineering Activates Pyrene‐Based Covalent Organic Frameworks for Efficient Photocatalytic Uranium Capture

Advanced Science, EarlyView.
A defect‐engineered pyrene‐based covalent organic framework (TP‐PYTO‐SA) is developed via strategic salicylaldehyde incorporation. This approach simultaneously enhances hydrophilicity and introduces uranyl coordination sites, while optimized defect density significantly improves charge separation.
Weikun Yao, Guanbing Zhou, Tao Liu, Yihui Yuan, Hui Wang, Ning Wang   +5 more
wiley   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Communication network security situation analysis based on time series data mining technology

Open Computer Science
Communication network security situation analysis prevents unauthorized users from accessing and stealing sensitive information. Network security analysis aims to monitor, discover, and eradicate security flaws by carefully examining the network’s ...
Jiang Qingjian
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Time Series Mining Approaches for Malaria Vector Prediction on Mid-Infrared Spectroscopy Data

Data Science Journal
Malaria is an infectious disease caused by the Plasmodium parasite transmitted to humans by the bite of infected female Anopheles mosquitoes. The disease remains a major cause of child mortality globally and caused more than 600,000 deaths in 85 ...
Lucas G. M. Castro, Henrique V. Costa, Vinicius M. A. Souza   +2 more
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Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

TIME SERIES ANALYSIS USING A UNIQUE MODEL OF TRANSFORMATION

Journal of Information and Organizational Sciences, 2007
REFII1 model is an authorial mathematical model for time series data mining. The main purpose of that model is to automate time series analysis, through a unique transformation model of time series.
Goran Klepac
doaj