Results 91 to 100 of about 50,820 (258)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Decomposition-Enhanced Network for financial time series forecasting
Scientific ReportsThe extreme non-stationarity, high noise levels, and multi-timescale coupling in financial futures markets pose major challenges for time series forecasting.
Jinyuan Huang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Recent Advances in Time Series Forecasting Methods
Applied SciencesTime series forecasting has become a key decision-support tool, with broad applicability within a series of domains within the economic field, among other fields [...]
Camelia Delcea
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Implementation of bagging in time series forecasting
Российский технологический журналObjectives. The purpose of the article is to build different models of bagging, to compare the accuracy of their forecasts for the test period against standard models, and to draw conclusions about the possibility of further use of the bagging technique ...
Ia. V. Gramovich +2 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Time series forecasting using the normalization model
Sistemnì Doslìdženâ ta Informacìjnì TehnologìïEmpirical constructions of time series models based on the reduction of initial data to normally distributed values have been proposed. The goal of a normalization method is to construct an optimal forecast that is linear for the updated data, and the ...
Viktor Bondarenko, Valeriia Bondarenko
doaj +1 more source