Results 101 to 110 of about 1,891,060 (279)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

An Improved GRU Financial Time Series Prediction Model

open access: yesFractal and Fractional
Forecasting financial time series (FTS) is essential for analyzing and understanding the dynamics of financial markets. Traditional recurrent neural network (RNN) models often suffer from low prediction accuracy on non-stationary and abruptly changing ...
Yong Li
doaj   +1 more source

Time Series Prediction : Predicting Stock Price

open access: yes, 2017
Under advisement of Dr. Sang Kim, for his class CS542.
Elliot, Aaron, Hsu, Cheng Hua
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Earthquake magnitude prediction based on artificial neural networks: A survey

open access: yesCroatian Operational Research Review, 2016
The occurrence of earthquakes has been studied from many aspects. Apparently, earthquakes occur without warning and can devastate entire cities in just a few seconds, causing numerous casualties and huge economic loss.
Emilio Florido   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

DeepONet-Inspired Architecture for Efficient Financial Time Series Prediction

open access: yesMathematics
Financial time series prediction is a fundamental problem in investment and risk management. Deep learning models, such as multilayer perceptrons, Convolutional Neural Networks (CNNs), and Long Short-Term Memory (LSTM), have been widely used in modeling ...
Zeeshan Ahmad, Shudi Bao, Meng Chen
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

CNN-Based Time Series Decomposition Model for Video Prediction

open access: yesIEEE Access
Video prediction presents a formidable challenge, requiring effectively processing spatial and temporal information embedded in videos. While recurrent neural network (RNN) and transformer-based models have been extensively explored to address spatial ...
Jinyoung Lee, Gyeyoung Kim
doaj   +1 more source

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