Results 51 to 60 of about 19,841,559 (252)

Time Series and Non-Time Series Models of Earthquake Prediction Based on AETA Data: 16-Week Real Case Study

Applied Sciences, 2022
The Key Laboratory of Integrated Microsystems (IMS) of Peking University Shenzhen Graduate School has deployed a self-developed acoustic and electromagnetics to artificial intelligence (AETA) system on a large scale and at a high density in China to ...
Chenyang Wang, Chaorun Li, Shanshan Yong, Xin’an Wang, Chao Yang   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Bootstrap prediction intervals in State Space models [PDF]

, 2008
Prediction intervals in state-space models can be obtained by assuming Gaussian innovations and using the prediction equations of the Kalman filter, with the true parameters substituted by consistent estimates. This approach has two limitations.
Ruiz Ortega, Esther, Ro Rodriguez, Esther Ruiz, Rodríguez, Alejandro, Ruiz, Esther   +4 more
core   +2 more sources

Chaotic Time Series Prediction Using Immune Optimization Theory [PDF]

International Journal of Computational Intelligence Systems, 2010
To solve chaotic time series prediction problem, a novel Prediction approach for chaotic time series based on Immune Optimization Theory (PIOT) is proposed.
Yuanquan Shi, Xiaojie Liu, Tao Li, Xiaoning Peng, Wen Chen, Ruirui Zhang, Yanming Fu   +6 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Multi-step ahead direct prediction for machine condition prognosis using regression trees and neuro-fuzzy systems [PDF]

, 2009
This paper presents an approach to predict the operating conditions of machine based on classification and regression trees (CART) and adaptive neuro-fuzzy inference system (ANFIS) in association with direct prediction strategy for multi-step ahead ...
Yang, Bo-Suk, Tan, Andy Chit Chiow, Tran, Van Tung, Tran, Van, Tan, Andy   +4 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Rainfall prediction in the northeast region of Thailand using Modular Fuzzy Inference System [PDF]

, 2012
In water management systems, accurate rainfall forecasting is indispensable for operation and management of reservoir, and flooding prevention because it can provide an extension of lead-time of the flow forecasting.
Wong, K.W., Fung, C.C., Chun Che Fung, Kok Wai Wong, Kajornrit, J., Jesada Kajornrit   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source