Results 111 to 120 of about 2,785,336 (285)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Emergent Time and Time Travel in Quantum Physics
UniverseEntertaining the possibility of time travel will invariably challenge dearly-held concepts in fundamental physics. It becomes relatively easy to construct multiple logical contradictions using differing starting points from various well-established ...
Ana Alonso-Serrano +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Time Travel, Alternate History, and Chronopolitics in the “The New Wave” of Chinese Science Fiction
Fafnir, 2023 The focus of this article is a small body of texts within “The New Wave” of Chinese science fiction, which emerged in the 1990s and 2000s. More specifically, I discuss two texts which can be regarded as variations of time travel and alternate history ...
Erik Mo Welin
doaj
Travel Time Variability After A Shock: The Case Of The Twin Cities Ramp Meter Shut Off [PDF]
Ramp meters in the Twin Cities were turned off for 8 weeks in the Fall of 2000. This paper analyzes travel time variability with and without ramp metering for several representative freeways during the afternoon peak period.
David Levinson, Lei Zhang
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Valuation of uncertainty in travel time and arrival time - some findings from a choice experiment [PDF]
We are developing a dynamic modeling framework in which we can evaluate the effects of different road pricing measures on individual choice behavior as well as on a network level.
Dirk Van Amelsfort, Michiel Bliemer
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Commuters’ valuation of travel time variability in Barcelona [PDF]
The value given by commuters to the variability of travel times is empirically analysed using stated preference data from Barcelona (Spain). Respondents are asked to choose between alternatives that differ in terms of cost, average travel time ...
Anna Matas, Javier Asensio
core