Results 231 to 240 of about 2,772,692 (284)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
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2022
Mental time travel research has given rise to an ongoing debate between causal and simulation theories of memory, which has, in turn, triggered a debate between continuist and discontinuist views of the relationship between remembering experienced past events and imagining possible future events.
Perrin, Denis +3 more
openaire +3 more sources
Mental time travel research has given rise to an ongoing debate between causal and simulation theories of memory, which has, in turn, triggered a debate between continuist and discontinuist views of the relationship between remembering experienced past events and imagining possible future events.
Perrin, Denis +3 more
openaire +3 more sources
Acta Mathematica Sinica, English Series, 2019
This paper is a survey of some results on travel time tomography. If the anisotropic index of refraction of a medium can be determined by measuring the travel times of waves going through the medium can be recast as geometry problems whose linearization versions lead to tensor tomography. The question is whether one can determine a symmetric two-tensor
Stefanov, Plamen D. +3 more
openaire +3 more sources
This paper is a survey of some results on travel time tomography. If the anisotropic index of refraction of a medium can be determined by measuring the travel times of waves going through the medium can be recast as geometry problems whose linearization versions lead to tensor tomography. The question is whether one can determine a symmetric two-tensor
Stefanov, Plamen D. +3 more
openaire +3 more sources