Results 61 to 70 of about 808,221 (264)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A New Varying-Parameter Design Formula for Solving Time-Varying Problems

Neural Processing Letters, 2020
A novel finite-time convergent zeroing neural network (ZNN) based on varying gain parameter for solving time-varying (TV) problems is presented. The model is based on the improvement and generalization of the finite-time ZNN (FTZNN) dynamics by means of the varying-parameter ZNN (VPZNN) dynamics, and termed as VPFTZNN.
Predrag S. Stanimirovic, Vasilios N. Katsikis, Dimitrios Gerontitis   +2 more
openaire   +2 more sources

Robust identification and control with time-varying parameter perturbations [PDF]

Proceedings of the 2003 American Control Conference, 2003., 2004
This paper is dedicated to the identification of parameters for a reasonably large class of nonlinear systems. We propose to design a direct parameter identification method in open loop and an indirect one in closed loop using the variable structure theory. The exponential convergence of parameter identifiers in both cases is studied.
Tarek Ahmed-Ali, Fabienne Floret, Françoise Lamnabhi-Lagarrigue   +2 more
openaire   +1 more source

Forecasting the Trend of Macroeconomic Variables in Terms of Financial Conditions Index in Iran: TVP-FAVAR Approach [PDF]

برنامه‌ریزی و بودجه, 2023
Due to the forward-looking nature of economic decisions, forecasting the trend of macroeconomic variables has a fundamental role in economic planning and policies. For this purpose, the present study attempts to extract the financial conditions index for
Atefe Alahverdi, Saeed Daei-Karimzadeh, Sara Ghobadi   +2 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Video Painting with Space-Time-Varying Style Parameters [PDF]

IEEE Transactions on Visualization and Computer Graphics, 2011
Artists use different means of stylization to control the focus on different objects in the scene. This allows them to portray complex meaning and achieve certain artistic effects. Most prior work on painterly rendering of videos, however, uses only a single painting style, with fixed global parameters, irrespective of objects and their layout in the ...
Mizuki Kagaya, William Brendel, Qingqing Deng, Todd Kesterson, Sinisa Todorovic, Patrick J. Neill, Eugene Zhang   +6 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A sliding window approach to optimize the time-varying parameters of a spatially-explicit and stochastic model of COVID-19. [PDF]

PLOS Glob Public Health, 2022
Ratnavale S, Hepp C, Doerry E, Mihaljevic JR.   +3 more
europepmc   +2 more sources

Time-varying hydrological simulation based on a SWD-SSC method

Journal of Hydrology: Regional Studies
Study region: The Fenhe River Basin, China Study focus: The hydrological parameters remained constant in a changing environment may no longer be applicable.
Jie Wang, Zhenxin Bao, Jianyun Zhang, Guoqing Wang, Cuishan Liu, Houfa Wu, Mingming Xie   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source