Results 61 to 70 of about 616 (261)

A theory of timed automata

open access: yesTheoretical Computer Science, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Rajeev Alur, David L. Dill
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Linear-Time Limited Automata [PDF]

open access: yesTheoretical Computer Science, 2018
The time complexity of 1-limited automata is investigated from a descriptional complexity view point. Though the model recognizes regular languages only, it may use quadratic time in the input length. We show that, with a polynomial increase in size and preserving determinism, each 1-limited automaton can be transformed into an halting linear-time ...
Bruno Guillon, Luca Prigioniero
openaire   +6 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Parametric, Probabilistic, Timed Resource Discovery System [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
This paper presents a fully distributed resource discovery and reservation system. Verification of such a system is important to ensure the execution of distributed applications on a set of resources in appropriate conditions. A semi-formal model for his
Camille Coti
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A Finite Representation of Durational Action Timed Automata Semantics

open access: yesMathematics
Durational action timed automata (daTAs) are state transition systems like timed automata (TAs) that capture information regarding the concurrent execution of actions and their durations using maximality-based semantics.
Ahmed Bouzenada   +2 more
doaj   +1 more source

Avoiding Shared Clocks in Networks of Timed Automata [PDF]

open access: yesLogical Methods in Computer Science, 2013
Networks of timed automata (NTA) are widely used to model distributed real-time systems. Quite often in the literature, the automata are allowed to share clocks, i.e.
Sandie Balaguer, Thomas Chatain
doaj   +1 more source

Fuzzy-Timed Automata [PDF]

open access: yes, 2010
Timed automata theory is well developed in literature. This theory provides a formal framework to model and test real-time systems. This formal framework supplies a way to describe transitions among states with timing constrains. These constraints are usually expressed with logic formulas involving the system clocks.
F. Javier Crespo   +2 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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