Results 71 to 80 of about 616 (261)

Timed Pushdown Automata Revisited [PDF]

open access: yes2015 30th Annual ACM/IEEE Symposium on Logic in Computer Science, 2015
full technical report of LICS'15 ...
Lorenzo Clemente, Slawomir Lasota 0001
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Revisiting reachability in timed automata [PDF]

open access: yes2017 32nd Annual ACM/IEEE Symposium on Logic in Computer Science (LICS), 2017
We revisit a fundamental result in real-time verification, namely that the binary reachability relation between configurations of a given timed automaton is definable in linear arithmetic over the integers and reals. In this paper we give a new and simpler proof of this result, building on the well-known reachability analysis of timed automata ...
Karin Quaas   +2 more
openaire   +4 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Abstraction of Dynamical Systems by Timed Automata [PDF]

open access: yesModeling, Identification and Control, 2011
To enable formal verification of a dynamical system, given by a set of differential equations, it is abstracted by a finite state model. This allows for application of methods for model checking. Consequently, it opens the possibility of carrying out the
Rafael Wisniewski, Christoffer Sloth
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Perturbed Timed Automata

open access: yes, 2005
We consider timed automata whose clocks are imperfect.
ALUR R   +2 more
openaire   +3 more sources

Better abstractions for timed automata [PDF]

open access: yesInformation and Computation, 2012
We consider the reachability problem for timed automata. A standard solution to this problem involves computing a search tree whose nodes are abstractions of zones. These abstractions preserve underlying simulation relations on the state space of the automaton.
Herbreteau, Frédéric   +2 more
openaire   +5 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Model Checking Techniques applied to the design of Web Services

open access: yesCLEI Electronic Journal, 2007
In previous work we have presented the generation of WS-CDL and WS-BPEL documents. In this paper we show the unification of both generations. The aim is to generate correct WS-BPEL skeleton documents from WS-CDL documents by using the Timed Automata as ...
Gregorio Dıaz   +4 more
doaj   +1 more source

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