Results 101 to 110 of about 234,786 (282)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

PENGARUH KEPEMILIKAN ASING DAN KEPEMILIKAN INSTITUSIONAL TERHADAP TIMELINESS LAPORAN KEUANGAN: Studi pada Perusahaan Manufaktur yang Terdaftar di BEI Tahun 2013-2015 [PDF]

, 2016
Tujuan penelitian ini adalah untuk mengetahui bagaimana pengaruh kepemilikan asing dan kepemilikan institusional baik secara parsial maupun simultan terhadap timeliness laporan keuangan pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia.
Hidayati, Annisa
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Relation between Changes in Audit Opinion and Financial Reporting Delay [PDF]

مطالعات تجربی حسابداری مالی, 2013
Timeliness is an important qualitative characteristic of financial information. The timeliness of information means that information should be provided to users in the shortest time and the fast way possible.
Zahra Hajiha, Mojtaba Fathi Moghadam
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Analysis and improvement of ZG off-line TTP non-repudiation protocol

Tongxin xuebao, 2009
Based on the weakness of ZG off-line TTP（trusted third party） non-repudiation protocol because of using pro-tocol deadline, the improvement of the ZG off-line TTP non-repudiation protocol was given, which eliminated the delay-ing resolve request attack ...
LIU Dong-mei1, QING Si-han 2, LI Peng-fei4, LI Shang-jie1   +3 more
doaj  

TIMELINESS ASSESSMENT FOR IMPLEMENTATION OF THE CRITICAL REQUESTS IN TWO-LEVEL CLUSTERS [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The paper deals with probability evaluation for timely service of requests in real-time systems at the time less than permitted limit in a two-level cluster where each incoming request is served first, in one of the bottom-level nodes and then in one of ...
A. V. Bogatyrev, V. A. Bogatyrev, S. V. Bogatyryev   +2 more
doaj  

PENGARUH PROFITABILITAS, UKURAN PERUSAHAAN DAN UKURAN KANTOR AKUNTAN PUBLIK (KAP) TERHADAP TIMELINESS LAPORAN KEUANGAN (Suatu Studi pada Sektor Properti, Real Estate dan Konstruksi Bangunan yang Terdaftar di Bursa Efek Indonesia Periode 2010-2014) [PDF]

, 2016
ABSTRAK Penelitian ini bertujuan untuk mengetahui, menggambarkan dan menjelaskan pengaruh besarnya profitabilitas, ukuran perusahaan dan ukuran KAP terhadap timeliness laporan keuangan yang terdaftar di Bursa Efek Indonesia periode 2010- 2014 ...
Aura Aulia Sibon Diandi, 114020187
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source