Results 121 to 130 of about 536,999 (233)

Boosting projection contrast method for co-aperture infrared optical engine design. [PDF]

iScience
Pan Y, Wang Z, Xu X, Xu L, Zhang Y, Sun S, Hu M.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Hematogones in CD34+ leukapheresis units: Is it important to quantify and report them? [PDF]

Hematol Transfus Cell Ther
Albuquerque RB, da Silva HL, Duarte FB, Matos DM.   +3 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Hand hygiene awareness and handwashing effectiveness in caregivers of surgical patients: a cross-sectional study. [PDF]

BMJ Open
Özer Özlü NG, Mutlu I, Köken S, Kılıçarslan B.   +3 more
europepmc   +1 more source

A Mixed Integer Linear Programming Approach to Minimum-Time Trajectory Generation Considering Traffic Lights for Class 8 Vehicles

IFAC-PapersOnLine
Jacob Ward, Evan Ellison, David Bevly, Lowell Brown   +3 more
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Nr2e3-Deficient Mice Show Evidence for Elevated Photoreceptor Bioenergetics and Retinal Visual Cycle Activity Based on OCT Metabolic Biomarkers. [PDF]

Invest Ophthalmol Vis Sci
Berkowitz BA, Podolsky RH, Burgoyne T, Hayes MJ, Katz R, Waseem R, Soetedjo J, Ataman ES, Roberts R.   +8 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

From Sunlight to Screens: Modeling When Light Exposure Matters Most for Sleep and Circadian Health. [PDF]

Clocks Sleep
Tavella F, Gradisar M, Lok R, Walch O.
europepmc   +1 more source