Results 171 to 180 of about 168,490,903 (279)
Minimum requirements for the design of Brazilian intensive care units: is it time for a change? [PDF]
Crit Care SciBarreto BB +3 more
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
, 1970 Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; Also available in an electronic version via the Internet at: http://nla.gov.
Howard, Bruce, 1936-
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Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
The car park and saddling paddock area at the Dajarra races, 1969 [picture] /
, 1969 Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; "The course had been cleared from scrubland" -- File 204/09/00042.; Also ...
Howard, Bruce, 1936-
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New Tradeoffs for Decremental Approximate All-Pairs Shortest Paths. [PDF]
AlgorithmicaDory M, Forster S, Nazari Y, de Vos T.
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
FEBS Open Bio, EarlyView.Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Bruce Howard photographing building sites in Melbourne in 1955 [picture].
, 1955 Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; Inscriptions: "Bruce Howard, Swanston St. building site, 1955."-- in ink on
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Circadian Biology and Phase Response: Fundamental Mechanisms and Clinical Applications. [PDF]
Clocks SleepMul Fedele ML, Cardinali DP.
europepmc +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source