Results 191 to 200 of about 958,468 (325)

Diagnosis and management of paediatric magnet ingestion: a systematic review of clinical practice guidelines. [PDF]

Emerg Med J
Nezhentsev A, Neville JJ, Hall NJ.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Why Camera-Based and Scale-Based Measurements Differ: A Physiological Model of Diurnal Weight Variation in Finishing Pigs. [PDF]

Animals (Basel)
Kawasue K, Win KD, Tokunaga T.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

AmpliRAD: A New Method Combining Amplicon and RAD Sequencing. [PDF]

Ecol Evol
Thompson TQ, Miller MR, Sloat MR.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Home-Based Learning Opportunities, Responsive Caregiving and the Development of Preschool-Aged Children in Low- and Middle-Income Countries of the East Asia and Pacific Region: A Systematic Review. [PDF]

Child Care Health Dev
Popplestone S, Honda T, Tran T, Baek Y, Romero L, Fisher J.   +5 more
europepmc   +1 more source

Variational Iteration Method for the Time-Fractional Elastodynamics of

, 2012
This paper presents the approximate analytical solutions to the time fractional differential equations of elasticity for 3D quasicrystals with initial conditions. These equations are written in the form of a vector partial differential equation of the second order.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Development of arrival-time diagnostic tool for X-ray pump-probe experiments at Shanghai Soft X-ray Free Electron Laser. [PDF]

J Synchrotron Radiat
Qiao Z, Fan J, Gao Z, Nie Y, Wen P, Wang X, Yan K, Ren H, Wang B, Jiang J, Shen Y, Zhang Y, Zhu W, Shu G, Xue C, Guo Z, Liu Z, Yang H, Qi Z, Zhang K, Liu T, Wang Z, Feng C, Tong Y, Liu Z, Jiang H.   +25 more
europepmc   +1 more source