Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cải tiến phương pháp phân tích thứ bậc sử dụng thuyết Dempster-Shafer
Phương pháp phân tích thứ bậc của Thomas Saaty có nhiệm vụ rất quan trọng trong việc xử lý thông tin để đưa ra quyết định lựa chọn, các phương án hành động tốt nhất, hợp lý nhất.
Phạm Minh Đương +2 more
doaj +1 more source
A new integral formula for supersymmetric scattering amplitudes in three dimensions
We propose a new integral formula for all tree-level scattering amplitudes of N=6 supersymmetric Chern-Simons theory. It resembles the Roiban-Spradlin-Volovich-Witten formula for N=4 supersymmetric Yang-Mills theory based on a twistor string theory ...
Huang, Yu-tin, Lee, Sangmin
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Some observations on the logical foundations of inductive theorem proving
In this paper we study the logical foundations of automated inductive theorem proving. To that aim we first develop a theoretical model that is centered around the difficulty of finding induction axioms which are sufficient for proving a goal. Based on
Hetzl, Stefan, Wong, Tin Lok
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
LỌC MÔ HÌNH ẢNH HƯỞNG TÚI TỪ TRỰC QUAN VÀ THUẬT TOÁN ARCX4-RMNB
Trong bài này, chúng tôi giới thiệu một phương pháp mới phát hiện những ảnh khiêu dâm dựa trên sự kết hợp giữa phương pháp biểu diễn ảnh bằng các nét đặc trưng không đổi với những biến đổi tỉ lệ (Scale-invariant feature transform ?
Nguyễn Minh Trung +2 more
doaj
Effects of Perinatal Exposure to Ketamine on the Developing Brain
Initially used as an analgesic and anesthetic, ketamine has unfortunately been abused as a popular recreational party drug due to its psychotropic effects. Over the last decade, ketamine has also emerged as an effective rapid-onset anti-depressant.
Hoi Man Cheung +3 more
doaj +1 more source
Friction and wear of selected metals and alloys in sliding contact with AISI 440 C stainless steel in liquid methane and in liquid natural gas [PDF]
Aluminum, titanium, beryllium, nickel, iron, copper, and several copper alloys were run in sliding contact with AISI 440C in liquid methane and natural gas.
Wisander, D. W.
core +1 more source

