Results 111 to 120 of about 120,333 (363)

Combined Immediate‐Release and Extended‐Release Formulation of Sodium Valproate Provides Stable Plasma Levels for Inhibition of Histone Deacetylation

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja, Susanna Kääriäinen, Zsófia Lovró, Mia Lundblad, Kristina Drott, Elsa Lilienberg, Marica T. Engström, Karla Saukkonen, Mika Scheinin   +8 more
wiley   +1 more source

Differences in characteristics between people with tinnitus that seek help and that do not

Scientific Reports, 2021
Knowledge on characteristics of people that seek help for tinnitus is scarce. The primary objective of this study was to describe differences in characteristics between people with tinnitus that seek help compared to those who do not seek help.
M. M. Rademaker, I. Stegeman, A. E. M. Brabers, J. D. de Jong, R. J. Stokroos, A. L. Smit   +5 more
doaj   +1 more source

When alarm bells ring: emergency tinnitus [PDF]

, 2016
OBJECTIVE: The aim of this study is to develop a diagnostic-therapeutic algorithm for those suffering from tinnitus who seek emergency aid. MATERIALS AND METHODS: A literature review has been performed on articles from the last 30 years. RESULTS: It is
Altissimi, Giancarlo, Cianfrone, Giancarlo, Ciofalo, Andrea, Greco, Antonio, Marinelli, C, Mazzei, F, Orlando, Maria Patrizia, Salviati, M, Testugini, C, Turchetta, Rosaria, Vincentiis, M. DE   +10 more
core  

The Dutch language version of the Toronto structured interview for Alexithymia: reliability, concurrent validity, and factor structure [PDF]

, 2013
The aim of this study was to evaluate the psychometric properties of the Dutch version of the Toronto Structured Interview for Alexithymia (TSIA) in a clinical sample.
Bagby, Michael, De Fruyt, Filip, Desmet, Mattias, Inslegers, Ruth, Meganck, Reitske, Ooms, Els, Taylor, Graeme, Vanheule, Stijn   +7 more
core   +3 more sources

Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti‐doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established

Drug Testing and Analysis, EarlyView.
From ingestion to hair incorporation Abstract The identification of trimetazidine, a medicine used for treating stable angina pectoris and for preventing angina attacks, has been recently observed in doping cases involving high profile athletes from various countries over the world.
Pascal Kintz, Alice Ameline, Laurie Gheddar   +2 more
wiley   +1 more source

Prevalence and associated risk factors of tinnitus among adult Palestinians: a cross-sectional study

Scientific Reports, 2022
Tinnitus is a common complaint with potentially negative impact on quality of life. Prevalence of tinnitus ranges from 5 to 43% worldwide. This variation could be due to the heterogeneity of tinnitus assessment.
Saad Al-Lahham, Zaher Nazzal, Ahmad Massarweh, Diana Saymeh, Sojoud Al-abed, Donia Muhammad, Raghda Alawni, Noor Bouzya, Malik Alqub, Mustafa Ghanim, Nael Ellahham   +10 more
doaj   +1 more source

WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Permanent Hearing Loss and Tinnitus

International Journal of Environmental Research and Public Health, 2017
Background: Hearing loss is defined as worsening of hearing acuity and is usually expressed as an increase in the hearing threshold. Tinnitus, defined as “ringing in the ear”, is a common and often disturbing accompaniment of hearing loss.
M. Śliwińska-Kowalska, Kamil Zaborowski   +1 more
semanticscholar   +1 more source

Noninvasive brain stimulation as focal epilepsy treatment in the hospital, clinic, and home

Epilepsia Open, EarlyView.
Abstract Objective Noninvasive brain stimulation (NIBS) provides a treatment option for patients not eligible for surgical intervention or who seek low‐risk approaches and may be used in the hospital, clinic, and at home. Our objective is to summarize our single‐center experience with multiple NIBS approaches for the treatment of focal epilepsy ...
Karimul Islam, Keith Starnes, Kelsey M. Smith, Thomas Richner, Nicholas Gregg, Alejandro A. Rabinstein, Gregory A. Worrell, Brian N. Lundstrom   +7 more
wiley   +1 more source

Clinical characteristics and psychoacoustic analysis of acute and chronic subjective tinnitus

Laryngoscope Investigative Otolaryngology, 2023
Objective This study aimed to understand the demographics, clinical characteristics, and psychoacoustic status of subjective tinnitus patients to explore the factors associated with acute and chronic tinnitus in the general hospitals of Shanghai. Methods
Haopeng Zhang, Lin Ji, Lihua Wang, Ziming Yin, Jingtu Cen, Yu Guo   +5 more
doaj   +1 more source

Decision support system to help choose between an ITE or a BTE hearing aid [PDF]

, 2011
A decision support system (DSS) is used for analysing a situation and making decisions. The goal of this research is to mine a large set of heterogeneous audiology data and create a DSS to help audiology technicians to choose between an ITE or BTE ...
Babi, Douglas, Gani, Kalakul
core   +1 more source