Results 21 to 30 of about 39,879 (232)

The progression of chronic tinnitus over the years

open access: yesScientific Reports, 2021
Little is known about the trajectory of tinnitus over time. This study addressed (1) how often tinnitus remitted in patients with chronic tinnitus; (2) how subjective reported tinnitus characteristics, such as loudness, laterality, and type and measures ...
Jorge P. Simões   +4 more
doaj   +1 more source

Natural history of tinnitus in adults: a cross-sectional and longitudinal analysis

open access: yesBMJ Open, 2020
Objective To assess incidence and changes in tinnitus and bothersome tinnitus as well as associated risk factors in a large sample of UK adults.Design Prospective cohort study.Setting UK.Participants For cross-sectional analysis, a group of 168 348 ...
Piers Dawes   +3 more
doaj   +1 more source

Experiential Characteristics among Individuals with Tinnitus Seeking Online Psychological Interventions: A Cluster Analysis

open access: yesBrain Sciences, 2022
Objective: This study was designed to gain insights regarding patterns of social representations (values, ideas, beliefs) of tinnitus and their relation to demographic and clinical factors.
Eldre W. Beukes   +4 more
doaj   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Embracing the psychological complexity of tinnitus-correlated distress: from descriptive nosology to person-centred explanatory models

open access: yesFrontiers in Psychiatry
Chronic tinnitus presents a psychosomatic paradox: while the perceptual characteristics of the sound are often similar across individuals and typically linked to hearing loss, the distress it evokes differs substantially.
Benjamin Boecking   +4 more
doaj   +1 more source

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

open access: yesAnnals of Neurology, EarlyView.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale   +17 more
wiley   +1 more source

Transdiagnostic dimensions of psychopathology in chronic tinnitus patients with and without hearing loss

open access: yesScientific Reports
Chronic tinnitus is frequently described as occurring with psychiatric comorbidities. However, this diagnosis-based framing may obscure underlying dimensions of psychological vulnerability in individuals both with and without measurable hearing loss (HL).
Benjamin Boecking   +4 more
doaj   +1 more source

Acoustic CR neuromodulation therapy for subjective tonal tinnitus: a review of clinical outcomes in an independent audiology practice setting

open access: yesFrontiers in Neurology, 2015
OBJECTIVE: To describe the quantitative treatment outcomes of patients undergoing acoustic coordinated reset (CR) neuromodulation at a single independent audiology practice over a 22 – 26 week period as part of an open label, non-randomized, non ...
Mark eWilliams   +2 more
doaj   +1 more source

Tinnitus characteristics in patients with idiopathic sudden sensorineural hearing loss and acute tinnitus

open access: yesLaryngoscope Investigative Otolaryngology, 2023
Objective Tinnitus is a common symptom of idiopathic sudden sensorineural hearing loss (ISSHL). This study aimed to investigate the characteristics and outcomes of acute tinnitus in patients with ISSHL. Methods A total of 59 patients with ISSHL and acute
Mohammad Mokhatrish   +3 more
doaj   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

open access: yesThe Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini   +8 more
wiley   +1 more source

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