Results 41 to 50 of about 63,282 (255)

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source

Acoustic CR neuromodulation therapy for subjective tonal tinnitus: a review of clinical outcomes in an independent audiology practice setting

Frontiers in Neurology, 2015
OBJECTIVE: To describe the quantitative treatment outcomes of patients undergoing acoustic coordinated reset (CR) neuromodulation at a single independent audiology practice over a 22 – 26 week period as part of an open label, non-randomized, non ...
Mark eWilliams, Christian eHauptmann, Nitesh ePAtel   +2 more
doaj   +1 more source

Natural history of tinnitus in adults: a cross-sectional and longitudinal analysis

BMJ Open, 2020
Objective To assess incidence and changes in tinnitus and bothersome tinnitus as well as associated risk factors in a large sample of UK adults.Design Prospective cohort study.Setting UK.Participants For cross-sectional analysis, a group of 168 348 ...
Piers Dawes, David Stockdale, David M Baguley, John Newall   +3 more
doaj   +1 more source

A scoping review of adverse events associated with concomitant beta‐adrenoreceptor blockers and selective serotonin reuptake inhibitors

British Journal of Clinical Pharmacology, EarlyView.
Beta‐adrenoreceptor blockers (beta‐blockers) and selective serotonin reuptake inhibitors (SSRIs) are commonly used medications and often used together, such as for the treatment of anxiety. However, there is no recent review of any potential adverse events related to concomitant use of medicines from each group.
Ziyi Cai, James Sutton, Charlotte Archer, Caroline S. Copeland, Joseph Hayes, Charles E. Leonard, Nicky Lidbetter, Kenneth K. C. Man, Faraz Mughal, Ian C. K. Wong, Hayley C. Gorton   +10 more
wiley   +1 more source

Unsupervised machine learning for multi‐system adverse event pattern detection in pharmacovigilance: A proof‐of‐concept analysis of fluoroquinolone reports in FAERS

British Journal of Clinical Pharmacology, EarlyView.
. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo, Sheikh S. Abdullah, Kamran Sedig, Flory T. Muanda   +3 more
wiley   +1 more source

A Systematic Review of the Safety and Tolerability of Theta Burst Stimulation in Children and Adolescents

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Theta burst stimulation (TBS) is often used in clinical practice and research protocols for adults with neuropsychiatric disorders. There are substantial knowledge gaps related to the application of TBS in children and adolescents.
Rana Elmaghraby, Qi Sun, Can Ozger, Julia Shekunov, Magdalena Romanowicz, Paul E. Croarkin   +5 more
wiley   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

Clinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit, Maaike van Dartel, Laura Rodwell, Hanneke van der Woude, Cornelis Boersma, Peter G. M. Mol, Doranne Hilarius   +6 more
wiley   +1 more source

Tinnitus school : an educational approach to tinnitus management based on a stress-reaction tinnitus model

, 2007
Stress is a significant factor influencing the clinical course of tinnitus. The auditory system is particularly sensitive to the effects of various stress factors (chemical, oxidative, emotional, etc.).
A. Cesarani, D. Alpini, A. Hahn
core   +2 more sources

Altered ABR Waveform Patterns in Tinnitus Patients With Normal Full-Frequency Hearing May Be Induced by Abnormal Middle Ear Muscle Activity Via the Trigeminal Nerve System

Journal of Otolaryngology - Head and Neck Surgery
Importance Evidence regarding the mechanism of tinnitus in patients with normal full-frequency hearing remains limited. This study investigated the auditory brainstem response (ABR) waveform patterns in these patients to address this unmet need, which is
Yun Jiang BM, Tianyi Ni MM, Hongbo Xie MM, Siyi Yang BM, Ziyuan Lin BM, Jian Ruan BM, Min Zhang PhD, Xiuling Lu BSN, Wenjing Zhang BS, Wenjing Su BS, Yuehong Liu PhD, Zhao Han PhD   +11 more
doaj   +1 more source

Metacognitive Interpersonal Therapy for Misophonia: A Single-Case Study

Brain Sciences
Background: Misophonia is a chronic condition in which the exposure to specific sounds increases the arousal and recurrence of specific intense negative emotions.
Eleonora Natalini, Alessandra Fioretti, Rebecca Eibenstein, Alberto Eibenstein   +3 more
doaj   +1 more source