Results 41 to 50 of about 39,879 (232)

Quality evaluation of information about sudden sensorineural hearing loss on TikTok videos: Cross-sectional study

Digital Health
Background Sudden sensorineural hearing loss (SSNHL) has increasingly become a critical public health concern worldwide, with limited access to health knowledge among Chinese patients.
Tianyi Ni, Yun Jiang, Yuehong Liu, Jing Zhou, Hongbo Xie, Siyi Yang, Jian Ruan, Dandan Guo, Ziyuan Lin, Zhao Han   +9 more
doaj   +1 more source

Candidate Key Proteins in Tinnitus—A Bioinformatic Study of Synaptic Transmission in the Cochlear Nucleus

Biomedicines
The aim of this study was to identify key proteins of synaptic transmission in the cochlear nucleus (CN) that are involved in normal hearing, acoustic stimulation, and tinnitus.
Johann Gross, Marlies Knipper, Birgit Mazurek   +2 more
doaj   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Impact of Temporomandibular Joint Complaints on Tinnitus-Related Distress

Frontiers in Neuroscience, 2019
There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been recently proposed that tinnitus patients with TMJ complaints could constitute a subtype, meaning a subgroup of tinnitus
Niklas K. Edvall, Edis Gunan, Eleni Genitsaridi, Eleni Genitsaridi, Andra Lazar, Golbarg Mehraei, Mattias Billing, Marie Tullberg, Jan Bulla, Jan Bulla, Jonathon Whitton, Barbara Canlon, Deborah A. Hall, Deborah A. Hall, Deborah A. Hall, Christopher R. Cederroth   +15 more
doaj   +1 more source

A first in disease trial of the safety, tolerability, and anti‐seizure effects of ES‐481 in drug‐resistant epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives ES‐481 is a novel potent and selective antagonist of TARP‐y8‐dependent AMPA receptors. We aimed to assess the potential efficacy, safety and tolerability, and pharmacokinetics of different doses of ES‐481 as an add‐on anti‐seizure medication (ASM) in adults with drug‐resistant epilepsy (DRE). Methods This was a Phase 2A double‐blind,
Emma C. Foster, Lyn Millist, Jack Germaine, Stephanie Chamorro, Caitlin Roberts, John‐Paul Nicolo, Sean Hosking, Piero Perucca, Saul Mullen, Heather Robinson, Rebecca Wharrie, Brittany Walsh, David Reutens, Kimberley Irwin, Hao Zeng, Robert Niecestro, Terence J. O'Brien   +16 more
wiley   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue, Yang Zhao, Huiying Sun, Hanlin Chen, Yong Zhao, Xin Ding, Wanru Zheng, Fei Ren, Yiwei Zhao, Jiajing Tong, Yu Chen, Zhiqiang Gao, Xu Tian, Siyi Cai, Guodong Feng   +14 more
wiley   +1 more source

Somatic Tinnitus

The International Tinnitus Journal, 2017
Modulation of tinnitus characteristics such as pitch and loudness has been extensively described following movements of the head, neck and limbs, vertical or horizontal eye gaze, pressure on myofascial trigger points, cutaneous stimulation of the hands, electrical stimulation of the median nerve, and transcranial direct current stimulation.
RALLI, MASSIMO, GRECO, Antonio, CIALENTE, FABRIZIO, DI STADIO, Arianna, DE VIRGILIO, ARMANDO, LONGO, Lucia, CIOFALO, Andrea, TURCHETTA, Rosaria, CIANFRONE, Giancarlo, DE VINCENTIIS, Marco   +9 more
openaire   +2 more sources

Clinical characteristics and psychoacoustic analysis of acute and chronic subjective tinnitus

Laryngoscope Investigative Otolaryngology, 2023
Objective This study aimed to understand the demographics, clinical characteristics, and psychoacoustic status of subjective tinnitus patients to explore the factors associated with acute and chronic tinnitus in the general hospitals of Shanghai. Methods
Haopeng Zhang, Lin Ji, Lihua Wang, Ziming Yin, Jingtu Cen, Yu Guo   +5 more
doaj   +1 more source

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

JEADV Clinical Practice, EarlyView.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro, Flaminia Antonelli, Dalma Malvaso, Federica Pellegrini, Elena Ippoliti, Niccolò Gori, Ketty Peris   +6 more
wiley   +1 more source

Aberrant cerebral blood flow in tinnitus patients with migraine: a perfusion functional MRI study

The Journal of Headache and Pain, 2021
Purpose Migraine is often accompanied with chronic tinnitus that will affect the cerebral blood flow (CBF) and exacerbate the tinnitus distress. However, the potential relationship between migraine and tinnitus remains unclear.
Zhen-Gui Xu, Jin-Jing Xu, Yu-Chen Chen, Jinghua Hu, Yuanqing Wu, Yuan Xue   +5 more
doaj   +1 more source