Results 41 to 50 of about 71,627 (246)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A Torsional Vibration Measurement Method for Rotating Blades Based on Blade Tip Timing

open access: yesShock and Vibration, 2021
During the working process of the turbine, some types of faults can cause changes in the vibration characteristics of the blades. The real-time vibration monitoring of the blades is of great significance to the stable operation and state-based ...
Haonan Guo   +6 more
doaj   +1 more source

Synchronous Vibration Parameter Recognition of Constant-Speed Blades Based on Blade Tip Clearance Measurement

open access: yesApplied Sciences, 2023
A new method for the synchronous vibration parameter identification of constant-speed rotating blades based on blade tip clearance (BTC) measurement and blade tip timing (BTT) is introduced.
Liang Zhang   +4 more
doaj   +1 more source

The tipping times in an Arctic sea ice system under influence of extreme events [PDF]

open access: yesChaos: An Interdisciplinary Journal of Nonlinear Science, 2020
<p>In light of the rapid recent retreat of Arctic sea ice, the extreme weather events triggering the variability in Arctic ice cover has drawn increasing attention. A non-Gaussian α-stable Lévy process is thought to be an appropriate model to describe such extreme events.
Fang Yang   +4 more
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Articulatory correlates of consonantal length contrasts: The case of Japanese mimetic geminates [PDF]

open access: yesJASA Express Letters
This study investigates the articulatory correlates of consonantal length contrasts in Japanese mimetic words using electromagnetic articulography data.
Francesco Burroni   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Design and Uncertainty Evaluation of a Calibration Setup for Turbine Blades Vibration Measurement

open access: yesSensors
Turbomachinery engines face significant failure risks due to the combination of thermal loads and high-amplitude vibrations in turbine and compressor blades.
Lorenzo Capponi   +8 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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