Results 41 to 50 of about 976,747 (262)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
International Journal of Rotating Machinery, 2007 Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. Although the fundamentals of the technique are simple, the analysis of data obtained in the presence of simultaneously occurring synchronous resonances is ...
J. Gallego-Garrido +2 more
doaj +1 more source
Analysis and Calibration of Blade Tip-Timing Vibration Measurement Under Variable Rotating Speeds
IEEE Access, 2021 Blade tip timing (BTT) vibration measurement is a promising on-line blade monitoring method, but various uncertainties bring great challenge in engineering applications. Most existing works are based on the assumption of constant rotating speeds. However,
Zhongsheng Chen +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
CNN-based defect diagnosis method for rotating blades
You-qi chuyun, 2020 In order to solve the problem of difficult blade defect diagnosis caused by severe signal under-sampling in tiptiming technology, a defect diagnosis method for rotating blade based on convolution neural network (CNN) was proposed.In the method, the under-
Jiwang ZHANG +3 more
doaj +1 more source
A Torsional Vibration Measurement Method for Rotating Blades Based on Blade Tip Timing
Shock and Vibration, 2021 During the working process of the turbine, some types of faults can cause changes in the vibration characteristics of the blades. The real-time vibration monitoring of the blades is of great significance to the stable operation and state-based ...
Haonan Guo +6 more
doaj +1 more source
The tipping times in an Arctic sea ice system under influence of extreme events [PDF]
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2020 <p>In light of the rapid recent retreat of Arctic sea ice, the extreme weather events triggering the variability in Arctic ice cover has drawn increasing attention. A non-Gaussian &#945;-stable L&#233;vy process is thought to be an appropriate model to describe such extreme events.
Fang Yang +4 more
openaire +4 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Articulatory correlates of consonantal length contrasts: The case of Japanese mimetic geminates [PDF]
JASA Express LettersThis study investigates the articulatory correlates of consonantal length contrasts in Japanese mimetic words using electromagnetic articulography data.
Francesco Burroni +2 more
doaj +1 more source
Applied Sciences, 2023 A new method for the synchronous vibration parameter identification of constant-speed rotating blades based on blade tip clearance (BTC) measurement and blade tip timing (BTT) is introduced.
Liang Zhang +4 more
doaj +1 more source