Results 61 to 70 of about 976,747 (262)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Time to Decide? Dynamical Analysis Predicts Partial Tip/Stalk Patterning States Arise during Angiogenesis. [PDF]

open access: yesPLoS ONE, 2016
Angiogenesis is a highly dynamic morphogenesis process; however, surprisingly little is known about the timing of the different molecular processes involved. Although the role of the VEGF-notch-DLL4 signaling pathway has been established as essential for
Lakshmi Venkatraman   +2 more
doaj   +1 more source

TiP

open access: yes, 2023
The replication package of TiP.
Anonymity (15421557)
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Effectiveness Analysis on Human-Machine Information Interaction of Intelligent Highway

open access: yesJournal of Advanced Transportation, 2022
Different human-machine collaboration modes and driving simulation tests with the orthogonal method considered are designed for a series of typical intelligent highway landscapes.
Yicheng Zhou   +7 more
doaj   +1 more source

Turbomachinery blade vibration amplitude measurement through tip timing with capacitance tip clearance probes [PDF]

open access: yes, 2005
Turbomachinery blade vibrations can cause High Cycle Fatigue, which reduces blade life. In order to observe this vibration a nonintrusive monitoring system is sought. The vibration can be detected by measuring blade tip timing since in the presence of
Lawson, Craig P., Ivey, Paul C.
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

BTT & RFLB - THE OPTIMUM SET FOR STEAM TURBINE BLADES MONITORING

open access: yesActa Polytechnica CTU Proceedings, 2018
BTT, Blade Tip Timing system, is a commercially available system generating files of precise times of blade tips when passing sensors attached in a machine stator.
Miroslav Balda
doaj   +1 more source

Advanced Noncontact Sensors for Blade Tip-Timing Systems

open access: yesJournal of Physics: Conference Series
Abstract The conference paper addresses noncontact sensors for measuring vibrations of machine blades using the Blade Tip Timing method. An overview of sensors based on the electromagnetic principle suitable for the harsh environment of low-pressure stages of steam turbines is presented.
Pavel Procházka   +2 more
openaire   +1 more source

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