Results 31 to 40 of about 213,394 (265)

Effect of the characteristics of granular media on dynamic penetration test - Numerical study using 2D - DEM

open access: yesEPJ Web of Conferences, 2017
The paper presents a numerical study on the influence of the properties of granular media on light dynamic penetration test results. A numerical model based on the Discrete Element Method (DEM) in 2 dimensions has been carried out.
Tran Quoc Anh   +2 more
doaj   +1 more source

Tipping Tumor Microenvironment against Drug Resistance

open access: yesJournal of Oncology Translational Research, 2017
Tumor microenvironment (TME) represents a structural hallmark of solid neoplasms, and plays a critical role in multiple aspects of oncologic pathogenesis such as local invasion and immune escaping, thus substantially contributing to malignant metastasis and anti-cancer drug resistance.
Daohong Chen, Xiaoshi Zhang
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Experimental Investigation of High Temperature-Resistant Inductive Sensor for Blade Tip Clearance Measurement

open access: yesSensors, 2018
Turbine tip clearance of aero-engine is important to engine performance. Proper control of rotor tip clearance contributes to engine efficiency improvement and fuel consumption reduction. Therefore, accurate tip clearance measurement is essential.
Ziyu Zhao   +3 more
doaj   +1 more source

Experimental Study on Post-Grouting Pile Vertical Bearing Performance Considering Different Grouting Methods and Parameters in Cohesive Soil

open access: yesApplied Sciences, 2023
The selection of grouting methods and parameters significantly affects the improvement in the pile-bearing capacity of cast-in-place bored piles. This study proposes a comprehensive set of test methods for constructing model piles, performing grouting at
Jiaqi Zhang, Chunfeng Zhao, Yue Wu
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

A method for predicting the influence of matric suction changes on CPT tip resistance [PDF]

open access: yesE3S Web of Conferences, 2019
The Cone Penetration Test (CPT) is a valuable tool for continuous soil profiling and estimating soil properties. A CPT sounding will often pass through the active zone of an unsaturated soil profile, near the ground surface where moisture conditions and ...
Miller Gerald A., Collins Rodney W.
doaj   +1 more source

Statistical analysis of CPT tip resistances

open access: yesPeriodica Polytechnica Civil Engineering, 2013
Selecting proper values for soil parameters is a crucial aspect in geotechnical engineering. Geomaterials exhibit an inherent, natural variability, which can be assessed by statistical methods. CPT data lend themselves well for statistical analysis, given the large amount of data retrieved in a single test.
openaire   +2 more sources

Improving wear resistance by electrolyte-plasma hardening of corrosion-resistant steel of the tip

open access: yesJournal of Applied Engineering Science, 2023
The development of new fields in the oil and gas industry of Kazakhstan, the exploitation of fields with hard-to-recover reserves, and the exclusion of harmful environmental impacts require the study of new advanced technologies in the manufacture of valves.
Kuat Kombayev   +3 more
openaire   +1 more source

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