Results 31 to 40 of about 75,283 (262)

DMST Approach for Analysis of 2 and 3 Bladed Type Darrieus Vertical Axis Wind Turbine

EAI Endorsed Transactions on Energy Web, 2020
Wind energy has lately been one of the world's leading outlets of clean energy for producing power in potential environments across the globe. Academics currently undertake numerous analysis practices to improve and refine current wind turbine designs ...
Sukanta Roga, Sudhir Kumar Dubey
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Aerodynamic Enhancement of Vertical-Axis Wind Turbines Using Plain and Serrated Gurney Flaps

Applied Sciences, 2023
In light of the escalating demand for renewable energy sources, vertical-axis wind turbines have emerged as a pivotal technical solution for addressing the challenge of clean energy supply in residential and urban areas.
Liu Chen, Pei Yang, Bingxia Zhang, Lingjie Chen   +3 more
doaj   +1 more source

Influence of Tip Speed Ratio on the efficiency of Savonius wind turbine with deformable blades

Journal of Physics: Conference Series, 2022
Abstract Improving machines efficiency and searching for their new applications are the main topics in the development of the renewable energy industry. In the case of Savonius type wind turbines, the works aim at the improvement of aerodynamic performance.
Emil Marchewka, Krzysztof Sobczak, Piotr Reorowicz, Damian Obidowski, Krzysztof Jóźwik   +4 more
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effects of geometry and tip speed ratio on the HAWT blade's root flow

Journal of Physics: Conference Series, 2014
In this study, the effect of the parameters playing a role in the root flow behavior of HAWT are only partly understood. To better reveal the root flow properties, this study presents the progression of HAWT blade root flow at two different blade geometries and at two different tip speed ratios.
Akay, B. (author), Micallef, D. (author), Simao Ferreira, C.J. (author), Van Bussel, G.J.W. (author)   +3 more
openaire   +4 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effect of the tip speed ratio on the wake characteristics of wind turbines using LBM‐LES

Energy Science & Engineering
In this paper, the wake characteristics of Zell 2000 wind turbine under different tip velocity ratios are studied by using the lattice Boltzmann method and large eddy simulation.
Xinghang Cui, Hantao Mao, Zhengdao Wang, Hui Yang, Yuehong Qian, Yikun Wei, Yan Zhang   +6 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source