Results 101 to 110 of about 4,530,863 (282)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan   +4 more
wiley   +1 more source

At “tipping point”: New report signals limited drive within the Home Office properly to address the Windrush scandal [PDF]

open access: yes
In a much anticipated independent review published on the Windrush scandal last week, Wendy Williams warns that the Home Office is at “tipping point” and must maintain momentum to ensure systemic and cultural ...
Hayes de kalaf, Eve, Cox, Juanita
core   +2 more sources

Tipping points v. talk about tipping points

open access: yes, 2007
Stevan Harnad, Tripping on Tipping Points: Jubilatio Praecox, <em> Open Access Archivangelism </em> , September 21, 2007.  Excerpt: <strong> Comment </strong> .  Well-put.  I made some of the same points in the September SOAN.
openaire   +1 more source

The implications of tipping for economics and management [PDF]

open access: yes
Tipping is a phenomenon that illustrates the importance of social norms and psychological reasons in motivating economic behavior. People tip because this is the social norm and disobeying norms results in psychological disutility.
Ofer H. Azar
core  

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich   +35 more
wiley   +1 more source

Understanding the Tipping Point of Urban Conflict: Global Policy Report

open access: yes, 2012
The purpose of this Report is to provide general policy recommendations from the four city studies undertaken for the research project 'Understanding the Tipping Point of Urban Conflict: Violence, Cities, and Poverty Reduction in the Development World ...
Rodgers, D.   +3 more
core  

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

Agentic AI for Automated Sensitivity Analysis of Missing Not at Random Data in Patient-Reported Outcome Measures: A Simulation Study

open access: yesEpidemiology, Biostatistics and Public Health
INTRODUCTION Patient-Reported Outcome Measures (PROMs) are central to evaluating surgical effectiveness. In the NHS England PROMs programme, only 27% of hip replacement episodes yielded post-operative responses in 2023/24.
Nicolò Cosimo Albanese
doaj   +1 more source

The Social Norm of Tipping: Does it Improve Social Welfare? [PDF]

open access: yes
Some economists believe that social norms are created to improve welfare where the market fails. I show that tipping is such a norm, using a model in which a waiter chooses service quality and then a customer chooses the tip.
Ofer H. Azar
core  

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