Results 161 to 170 of about 5,608 (193)
A simple, reversible and non-toxic anchor-away system for effective nuclear depletion of proteins
Esteban-Serna S +4 more
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Adenylate cyclase activity of TIR1/AFB auxin receptors in plants [PDF]
Nature, 2022 The phytohormone auxin is the major coordinative signal in plant development1, mediating transcriptional reprogramming by a well-established canonical signalling pathway. TRANSPORT INHIBITOR RESPONSE 1 (TIR1)/AUXIN-SIGNALING F-BOX (AFB) auxin receptors are F-box subunits of ubiquitin ligase complexes.
Linlin Qi +2 more
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Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 2007 Auxin is a pivotal plant hormone that controls many aspects of plant growth and development. Perceived by a small family of F-box proteins including transport inhibitor response 1 (TIR1), auxin regulates gene expression by promoting SCF ubiquitin-ligase-catalysed degradation of the Aux/IAA transcription repressors, but how the TIR1 F-box protein senses
Xu Tan +2 more
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The Arabidopsis F-box protein TIR1 is an auxin receptor
Nature, 2005 Despite 100 years of evidence showing a pivotal role for indole-3-acetic acid (IAA or auxin) in plant development, the mechanism of auxin perception has remained elusive. Central to auxin response are changes in gene expression, brought about by auxin-induced interaction between the Aux/IAA transcriptional repressor proteins and the ubiquitin-ligase ...
Stefan Kepinski +2 more
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Chemical hijacking of auxin signaling with an engineered auxin–TIR1 pair [PDF]
Nature Chemical Biology, 2018 The phytohormone auxin indole-3-acetic acid (IAA) regulates nearly all aspects of plant growth and development. Despite substantial progress in our understanding of auxin biology, delineating specific auxin response remains a major challenge. Auxin regulates transcriptional response via its receptors, TIR1 and AFB F-box proteins.
Naoyuki Uchida +2 more
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The F-box protein TIR1 is an auxin receptor
Nature, 2005The plant hormone auxin regulates diverse aspects of plant growth and development. Recent studies indicate that auxin acts by promoting the degradation of the Aux/IAA transcriptional repressors through the action of the ubiquitin protein ligase SCF(TIR1). The nature of the signalling cascade that leads to this effect is not known.
Nihal Dharmasiri +2 more
exaly +3 more sources
Molecular Plant, 2019 In Arabidopsis thaliana, canonical auxin-dependent gene regulation is mediated by 23 transcription factors from the AUXIN RESPONSE FACTOR (ARF) family that interact with auxin/indole acetic acid repressors (Aux/IAAs), which themselves form co-receptor ...
Abdellah Lakehal +2 more
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FERONIA-mediated TIR1/AFB2 oxidation stimulates auxin signaling in Arabidopsis
Molecular PlantThe phytohormone auxin plays a pivotal role in governing plant growth and development. Although the TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX (TIR1/AFB) receptors function in both the nucleus and cytoplasm, the mechanism governing the distribution of TIR1/AFBs between these cellular compartments remains unknown.
Chao Li
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Cloning and functional characterization of auxin receptor TIR1 in Gossypium hirsutum
Acta Physiologiae Plantarum, 2021Transport inhibitor response 1 (TIR1), as an F-box family protein, is a nucleus receptor of auxin in plants. It is essential in the auxin signal transduction pathway and the expression of auxin-responsive genes. As the most important hormone in plants, auxin has a great influence on the ovule and fiber development of cotton (Gossypium hirsutum L ...
Yu Wu +7 more
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