Results 171 to 180 of about 9,915 (200)

Adenylate cyclase activity of TIR1/AFB auxin receptors in plants

Nature, 2022
The phytohormone auxin is the major coordinative signal in plant development1, mediating transcriptional reprogramming by a well-established canonical signalling pathway. TRANSPORT INHIBITOR RESPONSE 1 (TIR1)/AUXIN-SIGNALING F-BOX (AFB) auxin receptors are F-box subunits of ubiquitin ligase complexes.
Linlin Qi, Mateusz Kwiatkowski, Scott A Sinclair   +2 more
exaly   +3 more sources

Mechanism of auxin perception by the TIR1 ubiquitin ligase

Nature, 2007
Auxin is a pivotal plant hormone that controls many aspects of plant growth and development. Perceived by a small family of F-box proteins including transport inhibitor response 1 (TIR1), auxin regulates gene expression by promoting SCF ubiquitin-ligase-catalysed degradation of the Aux/IAA transcription repressors, but how the TIR1 F-box protein senses
Xu Tan, Michal Sharon, Carol V Robinson   +2 more
exaly   +4 more sources

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The F-box protein TIR1 is an auxin receptor

Nature, 2005
The plant hormone auxin regulates diverse aspects of plant growth and development. Recent studies indicate that auxin acts by promoting the degradation of the Aux/IAA transcriptional repressors through the action of the ubiquitin protein ligase SCF(TIR1). The nature of the signalling cascade that leads to this effect is not known.
Nihal Dharmasiri, Sunethra Dharmasiri, Mark Estelle   +2 more
exaly   +3 more sources

The Arabidopsis F-box protein TIR1 is an auxin receptor

Nature, 2005
Despite 100 years of evidence showing a pivotal role for indole-3-acetic acid (IAA or auxin) in plant development, the mechanism of auxin perception has remained elusive. Central to auxin response are changes in gene expression, brought about by auxin-induced interaction between the Aux/IAA transcriptional repressor proteins and the ubiquitin-ligase ...
Stefan Kepiński, Ottoline Leyser
exaly   +3 more sources

Chemical hijacking of auxin signaling with an engineered auxin–TIR1 pair [PDF]

Nature Chemical Biology, 2018
The phytohormone auxin indole-3-acetic acid (IAA) regulates nearly all aspects of plant growth and development. Despite substantial progress in our understanding of auxin biology, delineating specific auxin response remains a major challenge. Auxin regulates transcriptional response via its receptors, TIR1 and AFB F-box proteins.
Naoyuki Uchida, Koji Takahashi, Seisuke Kimura   +2 more
exaly   +3 more sources

FERONIA-mediated TIR1/AFB2 oxidation stimulates auxin signaling in Arabidopsis

Molecular Plant
The phytohormone auxin plays a pivotal role in governing plant growth and development. Although the TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX (TIR1/AFB) receptors function in both the nucleus and cytoplasm, the mechanism governing the distribution of TIR1/AFBs between these cellular compartments remains unknown.
Chao Li
exaly   +3 more sources

Cloning and functional characterization of auxin receptor TIR1 in Gossypium hirsutum

Acta Physiologiae Plantarum, 2021
Transport inhibitor response 1 (TIR1), as an F-box family protein, is a nucleus receptor of auxin in plants. It is essential in the auxin signal transduction pathway and the expression of auxin-responsive genes. As the most important hormone in plants, auxin has a great influence on the ovule and fiber development of cotton (Gossypium hirsutum L ...
Yu Wu, Hainan Ming, Jing Xu, Jie Bing, Qing Chen, Qing Wang, Hongjie Li, Genfa Zhang   +7 more
openaire   +1 more source

The IAA1 protein is encoded by AXR5 and is a substrate of SCF^TIR1

The Plant Journal, 2004
SummaryRecent studies of auxin response have focused on the functions of three sets of proteins: the auxin (Aux) response factors (ARFs), the Aux/IAAs, and the F‐box protein TIR1. The ARF proteins bind DNA and directly activate or repress transcription of target genes while the Aux/IAA proteins repress ARF function.
Xiaoqing, Yang, Sungsu, Lee, Jai-Hyun, So, Suni, Dharmasiri, Nihal, Dharmasiri, Lei, Ge, Carolyn, Jensen, Roger, Hangarter, Lawrence, Hobbie, Mark, Estelle   +9 more
openaire   +2 more sources

Rational Design of an Auxin Antagonist of the SCF^TIR1 Auxin Receptor Complex

ACS Chemical Biology, 2012
The plant hormone auxin is a master regulator of plant growth and development. By regulating rates of cell division and elongation and triggering specific patterning events, indole 3-acetic acid (IAA) regulates almost every aspect of plant development. The perception of auxin involves the formation of a ternary complex consisting of an F-box protein of
Ken-ichiro, Hayashi, Joshua, Neve, Masakazu, Hirose, Atsuhito, Kuboki, Yukihisa, Shimada, Stefan, Kepinski, Hiroshi, Nozaki   +6 more
openaire   +2 more sources

miR393 inhibits in vitro shoot regeneration in Arabidopsis thaliana via repressing TIR1

Plant Science, 2018
A large number of genes are involved in the control of shoot regeneration from in vitro cultured plant material. The abundance of the miR393 was different between regenerable and non-regenerable calli induced from Arabidopsis thaliana explants. The regenerability of root explants derived from p35S:miR393a (the miR393a over-expressing line) was shown ...
Long, Wang, Zhenhua, Liu, Meng, Qiao, Fengning, Xiang   +3 more
openaire   +2 more sources