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The IAA1 protein is encoded by AXR5 and is a substrate of SCFTIR1
The Plant Journal, 2004SummaryRecent studies of auxin response have focused on the functions of three sets of proteins: the auxin (Aux) response factors (ARFs), the Aux/IAAs, and the F‐box protein TIR1. The ARF proteins bind DNA and directly activate or repress transcription of target genes while the Aux/IAA proteins repress ARF function.
Xiaoqing, Yang +9 more
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Rational Design of an Auxin Antagonist of the SCFTIR1 Auxin Receptor Complex
ACS Chemical Biology, 2012The plant hormone auxin is a master regulator of plant growth and development. By regulating rates of cell division and elongation and triggering specific patterning events, indole 3-acetic acid (IAA) regulates almost every aspect of plant development. The perception of auxin involves the formation of a ternary complex consisting of an F-box protein of
Ken-ichiro, Hayashi +6 more
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miR393 inhibits in vitro shoot regeneration in Arabidopsis thaliana via repressing TIR1
Plant Science, 2018A large number of genes are involved in the control of shoot regeneration from in vitro cultured plant material. The abundance of the miR393 was different between regenerable and non-regenerable calli induced from Arabidopsis thaliana explants. The regenerability of root explants derived from p35S:miR393a (the miR393a over-expressing line) was shown ...
Long, Wang +3 more
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Incidental thyroid carcinoma in patients with TIR1, TIR2 and TIR3 FNA.
Annali italiani di chirurgia, 2019The aim of our study was to evaluate the presence of incidental differentiated thyroid carcinomas, at final histological examination, in patients undergoing thyroidectomy or lobectomy for presumed benign pathology or in those with cytological diagnosis of indeterminate nodules (TIR3).457 patients who underwent surgery for benign disease and 179 ...
Angela, Pezzolla +6 more
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Adenylate cyclase activity of TIR1/AFB links cAMP to auxin-dependent responses
Molecular Plant, 2022Aloysius Wong +3 more
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Teaching resources. Model of the TIR1 pathway for auxin-mediated gene expression.
Science's STKE : signal transduction knowledge environment, 2006Auxin mediates numerous plant responses, some of which have been shown to require transcriptional regulation. One auxin response pathway, which depends on the relief of transcriptional repression, is mediated by TIR1 (transport inhibitor response protein 1). TIR1 is an auxin receptor and also a subunit of an SCF-type ubiquitin ligase.
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