Results 31 to 40 of about 5,608 (193)

Mutant analysis in Arabidopsis provides insight into the molecular mode of action of the auxinic herbicide dicamba. [PDF]

PLoS ONE, 2011
Herbicides that mimic the natural auxin indole-3-acetic acid are widely used in weed control. One common auxin-like herbicide is dicamba, but despite its wide use, plant gene responses to dicamba have never been extensively studied. To further understand
Cynthia Gleason, Rhonda C Foley, Karam B Singh   +2 more
doaj   +1 more source

A spontaneous TIR1 loss-of-function allele in C. elegans

microPublication biology, 2023
The auxin-inducible degron (AID) system is a widely-used system for conditional protein depletion. During the course of an experiment, we depleted the nuclear hormone receptor transcription factor NHR-23 to study molting, and we recovered a spontaneous suppressor allele that bypassed the L1 larval arrest caused by NHR-23 depletion.
Myles, Krista M., Vo, An A., Ragle, James Matthew, Ward, Jordan D.   +3 more
openaire   +2 more sources

The role of Phe82 and Phe351 in auxin-induced substrate perception by TIR1 ubiquitin ligase: a novel insight from molecular dynamics simulations. [PDF]

PLoS ONE, 2010
It is well known that Auxin plays a key role in controlling many aspects of plant growth and development. Crystal structures of Transport inhibitor response 1 (TIR1), a true receptor of auxin, were very recently determined for TIR1 alone and in complexes
Ge-Fei Hao, Guang-Fu Yang
doaj   +1 more source

Auxin-independent depletion of degron-tagged proteins by TIR1

microPublication biology, 2020
The auxin inducible degron (AID) system was developed to enable conditional depletion of proteins of interest. In this system, a plant-derived F-box protein, TIR1, is expressed and complexes with endogenous Skp1 and Cullin proteins to form an E3 ubiquitin ligase complex.
Schiksnis, Erin C, Nicholson, Angela L, Modena, Matthew S, Pule, Makena N, Arribere, Joshua A, Pasquinelli, Amy E   +5 more
openaire   +2 more sources

Design, Synthesis, and Action Mechanism of 1,3-Benzodioxole Derivatives as Potent Auxin Receptor Agonists and Root Growth Promoters

Frontiers in Plant Science, 2022
Deeper and longer roots allow crops to survive and flourish, but our understanding of the plant growth regulators promoting root system establishment is limited. Here, we report that, a novel auxin receptor agonist, named K-10, had a remarkable promotive
Zhikun Yang, Zhikun Yang, Jiahui Xu, Jiahui Xu, Lin Du, Jiaming Yin, Zhao Wang, Fei Yi, Liusheng Duan, Zhaohu Li, Baomin Wang, Kai Shu, Weiming Tan   +12 more
doaj   +1 more source

The co‐chaperone HOP participates in TIR1 stabilisation and in auxin response in plants

Plant, Cell & Environment, 2022
AbstractHOP (HSP70‐HSP90 organising protein) is a conserved family of co‐chaperones well known in mammals for its role in the folding of signalling proteins associated with development. In plants, HOP proteins have been involved in the response to multiple stresses, but their role in plant development remains elusive.
Alfonso Muñoz, Silvina Mangano, René Toribio, Lourdes Fernández‐Calvino, Juan C. del Pozo, M. Mar Castellano   +5 more
openaire   +4 more sources

A combinatorial TIR1/AFB–Aux/IAA co-receptor system for differential sensing of auxin [PDF]

, 2012
The plant hormone auxin regulates virtually every aspect of plant growth and development. Auxin acts by binding the F-box protein transport inhibitor response 1 (TIR1) and promotes the degradation of the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA ...
Calderón Villalobos, Luz Irina A, Zheng, Ning, Luz Irina A Calderón Villalobos, Parry, Geraint, Kepinski, Stefan, Estelle, Mark, Stefan Kepinski, Oliveira, Cesar de, Ning Zheng, Xu Tan, Sheard, Laura B., Luz Irina A. Calderón Villalobos, Wolfgang Brandt, Lynne Armitage, Napier, R. (Richard), Sarah Lee, Geraint Parry, Armitage, Lynne, Tan, Xu, Wolfgang Br, Brandt, Wolfgang, Laura B. Sheard, Haibin Mao, Mao, Haibin, Lee, Sarah C., Richard Napier, Laura B Sheard, Ivetac, Anthony, Cesar De Oliveira, Mark Estelle, Anthony Ivetac   +30 more
core   +1 more source

Defining binding efficiency and specificity of auxins for SCFTIR1/AFB-Aux/IAA co-receptor complex formation [PDF]

, 2014
Structure–activity profiles for the phytohormone auxin have been collected for over 70 years, and a number of synthetic auxins are used in agriculture. Auxin classification schemes and binding models followed from understanding auxin structures. However,
Evans, John P., Napier, R. (Richard), Ferro, N, Armitage, Lynne, Hawkes, Tim, Sundaram, S, Kepinski, S, Kepinski, Stefan, Lee, Sarah C., Hawkes, T, Armitage, L, Evans, JP, Sundaram, Shanthy, Napier, RM, Lee, S, Ferro, Noel   +15 more
core   +1 more source

MiR393 regulation of auxin signaling and redox-related components during acclimation to salinity in Arabidopsis. [PDF]

PLoS ONE, 2014
One of the most striking aspects of plant plasticity is the modulation of development in response to environmental changes. Plant growth and development largely depend on the phytohormone auxin that exerts its function through a partially redundant ...
María José Iglesias, María Cecilia Terrile, David Windels, María Cristina Lombardo, Carlos Guillermo Bartoli, Franck Vazquez, Mark Estelle, Claudia Anahí Casalongué   +7 more
doaj   +1 more source

Basic Protocol 1: Generation of eGFP-ARF-P2A-TIR1 or ARF-HA-P2A-TIR1 progenitor cells v1 [PDF]

, 2020
The first procedure for implementing the ARF-AID system is to establish ARF-TIR1 progenitor cells, as shown in Figure 2A. All the plasmids for integrating ARF-TIR1 into the AAVS1 locus in human cells are available from Addgene. The choice of transfection method varies depending on the cell type; lipofectamine 3000 works efficiently for HEK293T cells.
Kizhakke Mattada Sathyan, Thomas G. Scott, Michael J. Guertin   +2 more
openaire   +1 more source