Results 41 to 50 of about 5,608 (193)

Rapid and reversible root growth inhibition by TIR1 auxin signalling [PDF]

Nature Plants, 2018
The phytohormone auxin is the information carrier in a plethora of developmental and physiological processes in plants1. It has been firmly established that canonical, nuclear auxin signalling acts through regulation of gene transcription2. Here, we combined microfluidics, live imaging, genetic engineering and computational modelling to reanalyse the ...
Matyáš Fendrych, Maria Akhmanova, Jack Merrin, Matouš Glanc, Shinya Hagihara, Koji Takahashi, Naoyuki Uchida, Keiko U. Torii, Jiří Friml   +8 more
openaire   +2 more sources

A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice. [PDF]

PLoS Neglected Tropical Diseases, 2010
African trypanosomes are protozoan parasites that cause "sleeping sickness" in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection ...
Ian Goodhead, Alan Archibald, Peris Amwayi, Andy Brass, John Gibson, Neil Hall, Margaret A Hughes, Moses Limo, Fuad Iraqi, Stephen J Kemp, Harry A Noyes   +10 more
doaj   +1 more source

The eta7/csn3-3 auxin response mutant of Arabidopsis defines a novel function for the CSN3 subunit of the COP9 signalosome. [PDF]

PLoS ONE, 2013
The COP9 signalosome (CSN) is an eight subunit protein complex conserved in all higher eukaryotes. In Arabidopsis thaliana, the CSN regulates auxin response by removing the ubiquitin-like protein NEDD8/RUB1 from the CUL1 subunit of the SCF(TIR1/AFB ...
He Huang, Marcel Quint, William M Gray
doaj   +1 more source

TIR1-like auxin-receptors are involved in the regulation of plum fruit development [PDF]

Journal of Experimental Botany, 2014
Ethylene has long been considered the key regulator of ripening in climacteric fruit. Recent evidence showed that auxin also plays an important role during fruit ripening, but the nature of the interaction between the two hormones has remained unclear. To understand the differences in ethylene- and auxin-related behaviours that might reveal how the two
El-Sharkawy, Islam, Sherif, Sherif, Jones, Brian, Mila, Isabelle, Kumar, Prakash P., Bouzayen, Mondher, Jayasankar, Subramanian   +6 more
openaire   +6 more sources

Applying the auxin-based degron system for the inducible, reversible and complete protein degradation in Komagataella phaffii

iScience, 2022
Summary: The auxin-inducible degron (AID) system is a useful technique to rapidly deplete any protein of interest “on-demand.” In this study, we successfully established the AID system for the “biotech” yeast Komagataella phaffii.
Leonie Lehmayer, Lukas Bernauer, Anita Emmerstorfer-Augustin   +2 more
doaj   +1 more source

A super-sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair [PDF]

Nucleic Acids Research, 2020
Abstract The auxin-inducible degron (AID) system enables rapid depletion of target proteins within the cell by applying the natural auxin IAA. The AID system is useful for investigating the physiological functions of essential proteins; however, this system generally requires high dose of auxin to achieve effective depletion in ...
Nishimura, Kohei, Yamada, Ryotaro, Hagihara, Shinya, Iwasaki, Rie, Uchida, Naoyuki, Kamura, Takumi, Takahashi, Koji, Torii, Keiko U., Fukagawa, Tatsuo   +8 more
openaire   +2 more sources

HSP90 stabilizes auxin receptor TIR1 and ensures plasticity of auxin responses [PDF]

Plant Signaling & Behavior, 2017
Heat shock protein 90 (HSP90) is a highly conserved molecular chaperone that facilitates the maturation of target proteins. Here, we report that the auxin receptor TIR1 is a target of cytosolic HSP90 and that HSP90 and TIR1 form a complex. Inhibition of HSP90 compromised the nuclear localization of TIR1, and abrogated plant responses to the hormone ...
Etsuko Watanabe, Shoji Mano, Ikuko Hara-Nishimura, Mikio Nishimura, Kenji Yamada   +4 more
openaire   +3 more sources

Diversity and specificity: auxin perception and signaling through the TIR1/AFB pathway [PDF]

Current Opinion in Plant Biology, 2014
Auxin is a versatile plant hormone that plays an essential role in most aspects of plant growth and development. Auxin regulates various growth processes by modulating gene transcription through a SCF(TIR1/AFB)-Aux/IAA-ARF nuclear signaling module. Recent work has generated clues as to how multiple layers of regulation of the auxin signaling components
Wang, Renhou, Estelle, Mark
openaire   +4 more sources

Genome-wide association analysis reveals a novel pathway mediated by a dual-TIR domain protein for pathogen resistance in cotton

Genome Biology, 2023
Background Verticillium wilt is one of the most devasting diseases for many plants, leading to global economic loss. Cotton is known to be vulnerable to its fungal pathogen, Verticillium dahliae, yet the related genetic mechanism remains unknown. Results
Yihao Zhang, Yaning Zhang, Xiaoyang Ge, Yuan Yuan, Yuying Jin, Ye Wang, Lihong Zhao, Xiao Han, Wei Hu, Lan Yang, Chenxu Gao, Xi Wei, Fuguang Li, Zhaoen Yang   +13 more
doaj   +1 more source

Auxin canalization and vascular tissue formation by TIR1/AFB‐mediated auxin signaling in Arabidopsis [PDF]

New Phytologist, 2020
Summary Plant survival depends on vascular tissues, which originate in a self‐organizing manner as strands of cells co‐directionally transporting the plant hormone auxin. The latter phenomenon (also known as auxin canalization) is classically hypothesized to be regulated by auxin itself via the effect of this hormone on the polarity of its own ...
Mazur, Ewa, Kulik, Ivan, Hajný, Jakub, Friml, Jiří   +3 more
openaire   +6 more sources