Results 81 to 90 of about 13,850,387 (302)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Recommended Practice for Accepting New Concrete Pavement Surfaces for Tire/Pavement Noise, March 2, 2011 [PDF]

, 2011
This practice provides guidance and example specification language intended for use by Owner-Agencies in development of specific contract language when requiring the evaluation of tire/pavement noise for new concrete pavement surfaces.

core  

Experimental and numerical study of friction and braking characteristics of rolling tires

, 2011
Throughout the tire industry, virtual testing has been widely adopted in the design process. Both static deformation and dynamic response of the tire rolling on the road must be accurately predicted to evaluate the handling performance of a tire ...
Lopez Arteaga, Ines,, Schmeitz, A. J. C., Lopez, I., Nijmeijer, H., Schmeitz, A.J.C., A. Schmeitz, Steen, R. van der, I. Lopez, Lopez Arteaga, Ines, Van Der Steen, R., de Bruijn, B., B. de Bruijn, H. Nijmeijer, Bruijn, B. de, R. van der Steen   +14 more
core   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Deployment of Tire Pressure Monitoring Systems for Traffic Monitoring and Safety Purposes [PDF]

, 2011
In this paper, ideas and challenges of utilizing Tire Pressure Monitoring Systems’ (TPMS) communication messages for traffic purposes are described. Following the principle of the frequently and successfully tested Bluetooth technology approach to derive
Schulz, Jan, Junghans, Marek
core  

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

A Laminated Ring on Elastic Foundation Model and a Feedback Contact Algorithm for Tire-Road Contact Analysis

, 2017
This article proposes (1) a two-dimensional tire model that extends the deformable ring on elastic foundation (REF) model by treating the ring as a laminated beam and (2) a feedback compensation approach to solve the tire-road contact problem as ...
Chunjian Wang, Beshah Ayalew, John Adcox, Timothy Rhyne, Steve Cron   +4 more
core   +1 more source

Tire wear aware trajectory tracking control for Multi-axle Swerve-drive Autonomous Mobile Robots

Journal of Automation and Intelligence
Multi-axle Swerve-drive Autonomous Mobile Robots (MS-AMRs) equipped with independently steerable wheels are commonly used for high-payload transportation.
Tianxin Hu, Xinhang Xu, Thien-Minh Nguyen, Fen Liu, Shenghai Yuan, Lihua Xie   +5 more
doaj   +1 more source

A Novel Piecewise Affine Model for Vehicle Lateral Dynamics

IEEE Access, 2018
The lateral tire force is of crucial importance for the vehicle lateral dynamics modeling. Linear and nonlinear models have been proposed to describe the characteristic of the force.
Qian Zhang, Zhiyuan Liu
doaj   +1 more source

Estimation of Longitudinal Force, Sideslip Angle and Yaw Rate for Four-Wheel Independent Actuated Autonomous Vehicles Based on PWA Tire Model. [PDF]

Sensors (Basel), 2022
Sun X, Wang Y, Hu W.
europepmc   +1 more source