Results 101 to 110 of about 5,831,463 (318)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Tissue engineering of heart valves: advances and current challenges [PDF]

, 2009
It is estimated that the number of patients requiring heart valve replacement will triple over the next five decades. None of the current replacement valves can fully restore native valve function because they lack growth and remodeling capabilities ...
Baaijens, FPT Frank, Smits, A.I.P.M., Driessen-Mol, A Anita, Smits, AIPM Anthal, Driessen - Mol, A., Bouten, C.V.C., Bouten, C.V.C.; id_orcid, Bouten, CVC Carlijn, Baaijens, F.P.T., Smits, A.I.P.M.; id_orcid   +9 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Development and characterisation of a new bioink for additive tissue manufacturing [PDF]

, 2014
Additive manufacturing forms a potential route towards economically viable production of cellular constructs for tissue engineering. Hydrogels are a suitable class of materials for cell delivery and 3D culture, but are generally unsuitable as ...
Melchels, Ferry P. W., Dhert, Wouter J. a., ES TR, Tissue Repair, Faculteit Diergeneeskunde, Melchels, Ferry P.W., Sub General Pharmaceutics, Onderzoek, CSCA TR1, Malda, Jos, LS Equine Muscoskeletal Biology, Dhert, Wouter J.A., Hutmacher, Dietmar W.   +12 more
core   +1 more source

Analysis of rabbit cell surface (CD) antigens by means of cross-reactive monoclonal antibodies with specificity for cattle CD antigens

Czech Journal of Animal Science, 2009
Studies that involved testing monoclonal antibodies (mAbs) for cross-species reactivity proved to be efficient for the identification of previously unrecognized antigens in a number of different species.
M. Simon, J. Antalíková, Ľ. Horovská, J. Jankovičová, K. Fábryová, S. Hluchý, P. Chrenek, V. Tančin   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

BCTB FFPE (Formalin Fixed Paraffin Embedded) Blocks [PDF]

This BCTB tissue subcollection consists of FFPE (Formalin Fixed Paraffin Embedded) blocks: pieces of tissue fixed in formalin, dehydrated and embedded into wax, then thinly sliced for viewing under a microscope.

core  

Tissue-engineered heart valves develop native-like collagen fiber architecture [PDF]

, 2010
Creating autologous tissues with on-demand and native-like biomechanical properties is the ultimate challenge in functional heart valve tissue engineering.
Baaijens, FPT Frank, Kortsmit, J Jeroen, Bouten, C.V.C., Bouten, C.V.C.; id_orcid, Driessen, NJB Niels, Bouten, CVC Carlijn, Cox, MAJ Martijn, Kortsmit, J., Baaijens, F.P.T., Cox, M.A.J., Driessen, N.J.B.   +10 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

BCTB RNA Samples from Tissue [PDF]

This BCTB subcollection consists of RNA samples extracted from tissues in the ...

core