Results 111 to 120 of about 8,132,819 (307)
Targeting Strategies for the Combination Treatment of Cancer Using Drug Delivery Systems
Pharmaceutics, 2017 Cancer cells have characteristics of acquired and intrinsic resistances to chemotherapy treatment—due to the hostile tumor microenvironment—that create a significant challenge for effective therapeutic regimens.
Janel Kydd +5 more
doaj +1 more source
A level-set method for the evolution of cells and tissue during curvature-controlled growth
, 2019 Most biological tissues grow by the synthesis of new material close to the tissue's interface, where spatial interactions can exert strong geometric influences on the local rate of growth.
Guyot Y +4 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Panfacial trauma: management of a traumatic hemifacial avulsion and degloving injury with multiple maxillofacial fractures [PDF]
Archives of Trauma ResearchBackground: Cases of avulsion and degloving injuries of solitary areas of the face have been reported in the literature. However, complex traumatic degloving hemifacial injury with compound panfacial fractures is very rare.
Pulkit Khandelwal +4 more
doaj +1 more source
In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra [PDF]
, 2018 Premature cervical remodeling is a critical precursor of spontaneous preterm birth, and the remodeling process is characterized by an increase in tissue hydration.
Alisio, Mariana +31 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Journal of Medicinal Plants, 2018 Background: Obesity is one of the problems of major concern to todaychr('39')s society. Weight loss has been reported for Kelussia odoratissima Mozaff.
F Hashemi Shahraki +3 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Better than Real: Complex-valued Neural Nets for MRI Fingerprinting
, 2017 The task of MRI fingerprinting is to identify tissue parameters from complex-valued MRI signals. The prevalent approach is dictionary based, where a test MRI signal is compared to stored MRI signals with known tissue parameters and the most similar ...
Lustig, Michael +2 more
core +1 more source