Results 131 to 140 of about 6,381,755 (316)
BCTB FFPE (Formalin Fixed Paraffin Embedded) Blocks
This BCTB tissue subcollection consists of FFPE (Formalin Fixed Paraffin Embedded) blocks: pieces of tissue fixed in formalin, dehydrated and embedded into wax, then thinly sliced for viewing under a microscope.
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Spiral Tissue Microarrays as Next Evolutionary Step in the High-density Tissue Microarray Technology [PDF]
, 2010 Tissue microarray (TMA) is a well-established technique that connects basic research with clinical applications that allow the validation of many pathobiologic events from gene expression dysregulation to genomic aberrations.
Junya Fukuoka +7 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Modeling the Human Brain With ex vivo Slices and in vitro Organoids for Translational Neuroscience
Frontiers in Neuroscience, 2022 Giovanna O. Nogueira +5 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Breast Cancer Tissue Bank Blood Samples
This BCTB subcollection consists of blood samples taken from breast cancer patients and others. It is further broken down into a number of blood components.
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Linear viscoelastic behavior of subcutaneous adipose tissue
, 2008 Subcutaneous adipose tissue contributes to the overall mechanical behavior of the skin. Until today, however, no thorough constitutive model is available for this layer of tissue. As a start to the development of such a model, the objective of this study
Baaijens, FPT Frank +9 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Cytotoxicity measurements of tissue engineered scaffold
, 2018 Cytotoxicity measurements on materials are extremely important in tissue engineering field. The objective of this study is to measure and compare the cytotoxicity of scaffold for tissue engineered using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl ...
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