Results 151 to 160 of about 12,434,864 (335)
Modeling the Human Brain With ex vivo Slices and in vitro Organoids for Translational Neuroscience
Frontiers in Neuroscience, 2022 Giovanna O. Nogueira +5 more
doaj +1 more source
Apparatus and method of inserting a microelectrode in body tissue or the like using vibration means [PDF]
, 1979 An arrangement for and method of inserting a glass microelectrode having a tip in the micron range into body tissue is presented. The arrangement includes a microelectrode.
Crawford, D. W. +2 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Obesity is associated with macrophage accumulation in adipose tissue.
Journal of Clinical Investigation, 2003 S. Weisberg +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Macrophages in Tissue Repair, Regeneration, and Fibrosis.
Immunity, 2016 T. Wynn, K. Vannella
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
MR-metabolomics - towards the clinic?
Bioingeniøren, 2016 Background: Metabolomics is one of the fastest growing –omics technologies which is most representative for the phenotype of an organism at a specific time point.
Tonje H. Haukaas +4 more
doaj