Results 31 to 40 of about 139,523 (305)

Current approaches for modulation of the nanoscale interface in the regulation of cell behavior [PDF]

, 2018
Regulation of cell behavior in response to nanoscale features has been the focus of much research in recent years and the successful generation of nanoscale features capable of mimicking the natural nanoscale interface has been of great interest in the ...
Dalby, Matthew J., Donnelly, Hannah, Salmeron-Sanchez, Manuel, Sweeten, Paula E.   +3 more
core   +1 more source

Adhesions in the epidural space caused by frequent epidural blocks

JA Clinical Reports, 2017
We report a case of adhesions in the epidural space caused by more than 200 times epidural blocks that were observed with epiduroscopy. A 41-year-old man had repeatedly undergone lumbar epidural blocks to treat pain in his leg, resulting in decreased ...
Nobuhiro Shimada, Takashi Igarashi, Kunihiko Murai, Tetsuhito Hara, Tomoko Kuramochi, Mamoru Takeuchi   +5 more
doaj   +1 more source

Re-exploration of vertical rectus abdominis myocutaneous flap for vaginal reconstruction: Case report and review of the literature. [PDF]

, 2018
The vertical rectus abdominis myocutaneous (VRAM) flap is a versatile and well-established reconstructive technique for many defects created as a result of colorectal and gynecologic extirpation. However, major re-operation in the pelvis following a VRAM
Cohen, Joshua G, Festekjian, Jaco H, Kazanjian, Kevork K, Li, Andrew, Rouch, Joshua D   +4 more
core   +2 more sources

CaproGlu: Multifunctional tissue adhesive platform

Biomaterials, 2020
Driven by the clinical need for a strong tissue adhesive with elastomeric material properties, a departure from legacy crosslinking chemistries was sought as a multipurpose platform for tissue mending. A fresh approach to bonding wet substrates has yielded a synthetic biomaterial that overcomes the drawbacks of free-radical and nature-inspired ...
Djordjevic, Ivan, Pokholenko, Oleksandr, Shah, Ankur Harish, Wicaksono, Gautama, Blancafort, Lluis, Hanna, John V., Page, Samuel J., Nanda, Himansu Sekhar, Ong, Chee Bing, Chung, Sze Ryn, Chin, Andrew Yuan Hui, McGrouther, Duncan, Choudhury, Muntasir Mannan, Li, Fang, Teo, Jonathan Shunming, Lee, Lui Shiong, Steele, Terry W. J.   +16 more
openaire   +4 more sources

Pharmacological HIF-inhibition attenuates postoperative adhesion formation

Scientific Reports, 2017
Peritoneal adhesions represent a common complication of abdominal surgery, and tissue hypoxia is a main determinant in adhesion formation. Reliable therapeutic options to reduce peritoneal adhesions are scarce.
Moritz J. Strowitzki, Alina S. Ritter, Praveen Radhakrishnan, Jonathan M. Harnoss, Vanessa M. Opitz, Marvin Biller, Julian Wehrmann, Ulrich Keppler, Jana Scheer, Markus Wallwiener, Thomas Schmidt, Alexis Ulrich, Martin Schneider   +12 more
doaj   +1 more source

Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation

Blood Advances, 2019
Peritoneal adhesions are pathological fibroses that ensnare organs after abdominal surgery. This dense connective tissue can cause small bowel obstruction, female infertility, and chronic abdominal pain.
Jonathan M. Tsai, Maia Shoham, Nathaniel B. Fernhoff, Benson M. George, Kristopher D. Marjon, Melissa N. McCracken, Kevin S. Kao, Rahul Sinha, Anne Kathrin Volkmer, Masanori Miyanishi, Jun Seita, Yuval Rinkevich, Irving L. Weissman   +12 more
doaj   +1 more source

Designing stem cell niches for differentiation and self-renewal [PDF]

, 2018
Mesenchymal stem cells, characterized by their ability to differentiate into skeletal tissues and self-renew, hold great promise for both regenerative medicine and novel therapeutic discovery. However, their regenerative capacity is retained only when in
Dalby, Matthew J., Donnelly, Hannah, Salmeron-Sanchez, Manuel   +2 more
core   +1 more source

Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]

, 2017
The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C, Kaylan, Kerim B, Leckband, Deborah E, Underhill, Gregory H   +3 more
core   +1 more source

Meloxicam Decreases the Formation of Peritoneal Adhesions in an Experimental Surgical Model in Rats

International Journal of Medical Students, 2017
Background: Inflammatory adhesions result from an inflammatory response of the peritoneum during an intra-abdominal inflammatory process secondary to thermal or mechanical injury, infection, radiation, ischemia, dissection, abrasion or foreign body ...
Luis Alfredo Hernandez Villarroel, Henry Fernandez, Luisa Cesin   +2 more
doaj   +1 more source

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source