Results 91 to 100 of about 4,226,996 (321)

Surgical Management of Peripheral Ulcerative Keratitis: Update on Surgical Techniques and Their Outcome

Clinical Ophthalmology, 2022
Swapnali Sabhapandit,1 Somasheila I Murthy,2 Namrata Sharma,3 Virender S Sangwan4 1Institute of Ophthalmic Sciences, Asian Institute of Gastroenterology Hospitals, Hyderabad, Telangana, India; 2Tej Kohli Cornea Institute, L V Prasad Eye Institute, Kallam
Sabhapandit S, Murthy SI, Sharma N, Sangwan VS   +3 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Tough, self-healable and tissue-adhesive hydrogel with tunable multifunctionality

, 2017
An ideal hydrogel for biomedical engineering should mimic the intrinsic properties of natural tissue, especially high toughness and self-healing ability, in order to withstand cyclic loading and repair skin and muscle damage.
Lu Han, Liwei Yan, Kefeng Wang, Liming Fang, Hongping Zhang, Youhong Tang, Yonghui Ding, L. Weng, Jielong Xu, J. Weng, Yu-jie Liu, Fuzeng Ren, Xiong Lu   +12 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Low cytotoxic tissue adhesive based on oxidized dextran and epsilon‐poly‐l‐lysine [PDF]

, 2013
Suong‐Hyu Hyon, Naoki Nakajima, Hajime Sugai, Kazuaki Matsumura   +3 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction

International Archives of Otorhinolaryngology
Introduction An ideal and long-lasting adhesive and sealant is essential during endoscopic endonasal skull-base surgery to hold the reconstruction intact and prevent cerebrospinal fluid (CSF) permeation until complete healing occurs.
Ashwin Gajendran Vedhapoodi, Aravind Sabesan, Benazir Ferozkhan, Saravana Selvan Velmurugan, Venkatesan Rajarajan, Baskar Arukavur Radhakrishnan, Kanagaraman Prabhuraman, Bhuvaneswari Natarajan   +7 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Charge balance transition enabled Janus hydrogel for robust wet-tissue adhesion and anti-postoperative adhesion

Bioactive Materials
Janus hydrogels have recently emerged as promising bioadhesives for efficient wet-tissue adhesion and anti-postoperative adhesion. However, existing Janus hydrogel adhesives normally need varied chemical designs of different layers to achieve asymmetric ...
Wan Peng, Youjin Lai, Yefeng Jiang, Yang Zhang, Zilin Kan, Chuanchao Dai, Jian Shen, Pingsheng Liu   +7 more
doaj   +1 more source

In vitro and in vivo tissue repair with laser‐activated chitosan adhesive [PDF]

, 2006
Antonio Lauto, Marcus A. Stoodley, H. Tempelaars Marcel, Alberto Avolio, Maria Sarris, Gavin McKenzie, David D. Sampson, L. John R. Foster   +7 more
openalex   +1 more source