Results 31 to 40 of about 140,038 (262)

Locally Administered Photodynamic Therapy for Cancer Using Nano-Adhesive Photosensitizer

Pharmaceutics, 2023
Photodynamic therapy (PDT) is a great potential anti-tumor therapy owing to its non-invasiveness and high spatiotemporal selectivity. However, systemically administered photosensitizers diffuse in the skin and the eyes for a long duration, which cause ...
Yoshiki Komatsu, Toru Yoshitomi, Van Thi Hong Doan, Hiromi Kurokawa, Saori Fujiwara, Naoki Kawazoe, Guoping Chen, Hirofumi Matsui   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Use of Cyanoacrylate Tissue Adhesives in Various Wound Suturing Techniques to Enhance the Healing Process of Surgical Wounds: An Animal Study

Clinical and Experimental Dental Research
Objectives This study aimed to investigate the effect of cyanoacrylate tissue adhesive and suture techniques on closing surgical wounds in rabbits. Materials and Methods This study randomly divided 32 male New Zealand white rabbits into four groups.
Mojtaba Alijani, Shokofeh Jamshidi, Reza Nadripour, Naser Kamyari, Ali Heidari   +4 more
doaj   +1 more source

Comparative evaluation of a novel adhesive- Histoweld™ for immunohistochemistry: A non-inferiority study

Indian Journal of Pathology and Microbiology
Objectives: To evaluate the performance of adhesive I (Histoweld™) and compare it with routinely used adhesive II (poly-l-lysine). Materials and Methods: A total of 33 routinely used immunohistochemistry (IHC) antibodies specific for 11 different organs ...
Kanishk Gupta, Surbhi Goyal, Puja Sakhuja, Neelam Negi   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

In-vitro evaluation of antibacterial potential of cyanoacrylate tissue adhesives for intraoral wound closure [PDF]

Journal of Dental Materials and Techniques, 2017
Background: Cyanoacrylate tissue adhesives have been used as a substitute to silk for intraoral wound closure. Placement of sutures provides a corridor for accumulation of microorganisms into tissue which leads to infection. Cyanoacrylate-based adhesives
Murtaza A Kaderi, K.B Menaka, Renuka M Metgud, Mugdha R Gharat, Priyanka S Naik, Jyoti M Ajbani, Pooja P Naik, Aditi Mahajani   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Cyanoacrylate: An alternative to silk sutures: A comparative clinical study

Journal of Dr. NTR University of Health Sciences, 2018
Aim: The aim of the study is to compare silk sutures and n-butyl-2-cyanoacrylate tissue adhesive in intraoral wound closure and contrast the effects through the assessment of time taken to close the wound, time taken for securing hemostasis ...
Phani Himaja Devi Vaaka, Bal Reddy Patlolla, Sai Kiran Donga, Aruna Kumari Ganapathi, Vamsilatha Kurapati   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source